Chlorine in PDB 3sm9: Crystal Structure of Metabotropic Glutamate Receptor 3 Precursor in Presence of LY341495 Antagonist

The structure of Crystal Structure of Metabotropic Glutamate Receptor 3 Precursor in Presence of LY341495 Antagonist, PDB code: 3sm9 was solved by A.K.Wernimont, A.Dong, A.Seitova, L.Crombet, G.Khutoreskaya, A.M.Edwards, C.H.Arrowsmith, C.Bountra, J.Weigelt, D.Cossar, E.Dobrovetsky, Structuralgenomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.84 / 2.26
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	83.402, 98.633, 203.513, 90.00, 90.00, 90.00
R / Rfree (%)	20.1 / 22.7

The binding sites of Chlorine atom in the Crystal Structure of Metabotropic Glutamate Receptor 3 Precursor in Presence of LY341495 Antagonist (pdb code 3sm9). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Metabotropic Glutamate Receptor 3 Precursor in Presence of LY341495 Antagonist, PDB code: 3sm9:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Metabotropic Glutamate Receptor 3 Precursor in Presence of LY341495 Antagonist


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Metabotropic Glutamate Receptor 3 Precursor in Presence of LY341495 Antagonist within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl486 b:39.3 occ:1.00 OG1 A:THR73 2.9 38.1 1.0 N A:SER124 3.3 34.1 1.0 CG1 A:VAL128 3.6 40.4 1.0 CB A:THR73 3.7 39.7 1.0 CG2 A:THR73 3.7 34.5 1.0 N A:TYR125 3.7 36.2 1.0 CB A:SER124 3.8 36.8 1.0 CB A:VAL128 3.9 41.4 1.0 CB A:PRO21 3.9 34.1 1.0 CG2 A:VAL128 3.9 40.3 1.0 CD1 A:TYR125 3.9 40.4 1.0 CD A:PRO21 3.9 34.8 1.0 CA A:SER124 4.0 34.1 1.0 N A:PRO21 4.0 33.2 1.0 CG A:PRO21 4.1 38.3 1.0 CA A:GLY123 4.3 35.2 1.0 C A:GLY123 4.3 37.3 1.0 CA A:PRO21 4.3 32.6 1.0 C A:SER124 4.3 39.1 1.0 OG A:SER124 4.5 42.9 1.0 C A:PHE20 4.5 36.9 1.0 CB A:TYR125 4.6 37.7 1.0 CA A:TYR125 4.7 36.3 1.0 CE1 A:TYR125 4.7 42.6 1.0 CG A:TYR125 4.7 38.6 1.0 CA A:SER75 4.8 44.1 1.0 O A:TYR125 4.9 40.8 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Metabotropic Glutamate Receptor 3 Precursor in Presence of LY341495 Antagonist


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Metabotropic Glutamate Receptor 3 Precursor in Presence of LY341495 Antagonist within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl487 b:72.0 occ:1.00 CAK A:Z99485 3.7 46.9 1.0 N A:TYR197 3.7 53.1 1.0 N A:ASP196 3.8 58.3 1.0 O A:HOH562 4.0 85.9 1.0 CB A:TYR197 4.0 50.2 1.0 CA A:GLY195 4.1 59.9 1.0 C A:GLY195 4.1 62.3 1.0 CAG A:Z99485 4.3 48.3 1.0 CD A:ARG252 4.4 68.8 1.0 O A:GLU194 4.4 66.7 1.0 CA A:TYR197 4.5 51.7 1.0 CA A:ASP196 4.5 57.8 1.0 CB A:ASP196 4.6 60.0 1.0 C A:ASP196 4.6 58.7 1.0 CAT A:Z99485 4.8 50.1 1.0 OAP A:Z99485 4.9 46.9 1.0 O A:GLY195 4.9 61.8 1.0

A.K.Wernimont, A.Dong, A.Seitova, L.Crombet, G.Khutoreskaya, A.M.Edwards, C.H.Arrowsmith, C.Bountra, J.Weigelt, D.Cossar, E.Dobrovetsky. Crystal Structure of Metabotropic Glutamate Receptor 3 Precursor in Presence of LY341495 Antagonist To Be Published.