Chlorine in PDB 3toa: Human Mof Crystal Structure with Active Site Lysine Partially Acetylated

All present enzymatic activity of Human Mof Crystal Structure with Active Site Lysine Partially Acetylated:
2.3.1.48;

The structure of Human Mof Crystal Structure with Active Site Lysine Partially Acetylated, PDB code: 3toa was solved by H.Yuan, E.C.Ding, R.Marmorstein, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.23 / 3.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	46.255, 58.534, 121.501, 90.00, 90.00, 90.00
R / Rfree (%)	24.6 / 26.5

The structure of Human Mof Crystal Structure with Active Site Lysine Partially Acetylated also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Chlorine atom in the Human Mof Crystal Structure with Active Site Lysine Partially Acetylated (pdb code 3toa). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Human Mof Crystal Structure with Active Site Lysine Partially Acetylated, PDB code: 3toa:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Human Mof Crystal Structure with Active Site Lysine Partially Acetylated


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Mof Crystal Structure with Active Site Lysine Partially Acetylated within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl502 b:52.3 occ:1.00 N A:ASP190 3.3 53.6 1.0 CA A:ILE189 3.8 35.7 1.0 OD2 A:ASP190 4.0 60.1 1.0 CG2 A:ILE189 4.0 36.9 1.0 C A:ILE189 4.1 36.3 1.0 O A:GLU188 4.1 56.7 1.0 CG A:ASP190 4.1 58.1 1.0 CB A:ASP190 4.2 52.0 1.0 CA A:ASP190 4.3 51.9 1.0 CB A:ILE189 4.5 37.2 1.0 O A:ASP190 4.7 55.5 1.0 N A:ILE189 4.8 36.8 1.0 OD1 A:ASP190 4.8 58.3 1.0 C A:GLU188 4.8 55.2 1.0

Chlorine binding site 2 out of 2 in the Human Mof Crystal Structure with Active Site Lysine Partially Acetylated


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Human Mof Crystal Structure with Active Site Lysine Partially Acetylated within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl503 b:81.6 occ:1.00 O A:SER222 2.6 44.3 1.0 C A:SER222 3.4 44.4 1.0 CD2 A:PHE225 3.6 48.2 1.0 N A:HIS226 3.7 64.3 1.0 CA A:SER222 3.7 45.1 1.0 CB A:HIS226 3.7 64.3 1.0 CB A:SER222 3.7 45.1 1.0 CB A:PHE225 4.0 47.3 1.0 CA A:HIS226 4.1 63.3 1.0 CG A:PHE225 4.3 48.5 1.0 SD A:MET217 4.3 53.9 1.0 C A:PHE225 4.5 49.7 1.0 CE2 A:PHE225 4.6 49.6 1.0 N A:TYR223 4.7 54.9 1.0 ND1 A:HIS226 4.7 63.8 1.0 CG A:HIS226 4.7 64.1 1.0 OG A:SER222 4.7 48.0 1.0 CA A:PHE225 4.7 48.9 1.0 CE A:LYS215 4.9 49.5 1.0

H.Yuan, D.Rossetto, H.Mellert, W.Dang, M.Srinivasan, J.Johnson, S.Hodawadekar, E.C.Ding, K.Speicher, N.Abshiru, R.Perry, J.Wu, C.Yang, Y.G.Zheng, D.W.Speicher, P.Thibault, A.Verreault, F.B.Johnson, S.L.Berger, R.Sternglanz, S.B.Mcmahon, J.Cote, R.Marmorstein. Myst Protein Acetyltransferase Activity Requires Active Site Lysine Autoacetylation. Embo J. V. 31 58 2011.
ISSN: ISSN 0261-4189
PubMed: 22020126
DOI: 10.1038/EMBOJ.2011.382