Atomistry » Chlorine » PDB 3txf-3u5y » 3txk
Atomistry »
  Chlorine »
    PDB 3txf-3u5y »
      3txk »

Chlorine in PDB 3txk: Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5

Enzymatic activity of Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5

All present enzymatic activity of Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5:
3.2.1.17;

Protein crystallography data

The structure of Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5, PDB code: 3txk was solved by S.W.M.Tanley, A.M.M.Schreurs, J.R.Helliwell, L.M.J.Kroon-Batenburg, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 33.51 / 3.00
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 79.460, 79.460, 36.960, 90.00, 90.00, 90.00
R / Rfree (%) 21.1 / 25.9

Other elements in 3txk:

The structure of Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5 also contains other interesting chemical elements:

Platinum (Pt) 2 atoms
Sodium (Na) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5 (pdb code 3txk). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 7 binding sites of Chlorine where determined in the Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5, PDB code: 3txk:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7;

Chlorine binding site 1 out of 7 in 3txk

Go back to Chlorine Binding Sites List in 3txk
Chlorine binding site 1 out of 7 in the Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1130

b:60.9
occ:1.00
 OH A:TYR23 3.0 37.3 1.0
CE2 A:TYR23 3.4 38.1 1.0
CA A:GLY104 3.6 39.8 1.0
CZ A:TYR23 3.7 37.3 1.0
N A:GLY104 4.3 40.9 1.0
CD2 A:TYR23 4.6 36.2 1.0
O A:ARG21 4.8 41.8 1.0
C A:GLY104 4.9 38.2 1.0

Chlorine binding site 2 out of 7 in 3txk

Go back to Chlorine Binding Sites List in 3txk
Chlorine binding site 2 out of 7 in the Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1131

b:77.8
occ:1.00
 OG A:SER24 3.1 36.9 1.0
N A:GLY26 3.2 37.4 1.0
CA A:GLY26 3.3 37.0 1.0
CA A:GLN121 3.3 48.2 1.0
N A:GLN121 3.6 46.2 1.0
CD1 A:ILE124 3.8 41.8 1.0
CB A:SER24 3.8 39.4 1.0
CB A:GLN121 3.9 50.7 1.0
CG1 A:VAL120 4.2 41.0 1.0
C A:VAL120 4.3 44.5 1.0
C A:GLY26 4.4 35.2 1.0
CG1 A:ILE124 4.5 43.5 1.0
C A:LEU25 4.5 36.7 1.0
N A:ASN27 4.5 34.7 1.0
N A:LEU25 4.5 38.9 1.0
C A:SER24 4.5 37.7 1.0
C A:GLN121 4.6 48.7 1.0
CB A:VAL120 4.6 42.1 1.0
O A:VAL120 4.6 44.4 1.0
O A:SER24 4.8 36.4 1.0
O A:GLN121 4.8 49.7 1.0
CA A:SER24 4.9 38.5 1.0

Chlorine binding site 3 out of 7 in 3txk

Go back to Chlorine Binding Sites List in 3txk
Chlorine binding site 3 out of 7 in the Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1132

b:23.8
occ:1.00
 N A:THR69 3.5 44.1 1.0
NA A:NA1138 3.5 23.5 1.0
OG A:SER72 3.5 45.0 1.0
OD1 A:ASP66 3.6 38.8 1.0
O A:THR69 3.6 44.5 1.0
N A:ARG68 3.7 44.7 1.0
N A:GLY67 3.8 42.5 1.0
CB A:THR69 3.9 40.9 1.0
CA A:GLY67 3.9 44.5 1.0
C A:GLY67 3.9 45.5 1.0
C A:THR69 3.9 45.2 1.0
CA A:THR69 4.0 43.4 1.0
C A:ARG68 4.5 44.8 1.0
CA A:ARG68 4.6 46.3 1.0
OG1 A:THR69 4.6 40.2 1.0
N A:ASP66 4.7 39.7 1.0
CB A:SER72 4.7 44.4 1.0
O A:GLY67 4.8 47.5 1.0
OD1 A:ASN65 4.8 43.8 1.0
CG A:ASP66 4.8 37.9 1.0
N A:PRO70 4.8 47.4 1.0
C A:ASP66 4.9 41.2 1.0
N A:SER72 5.0 47.5 1.0
CG2 A:THR69 5.0 40.8 1.0

Chlorine binding site 4 out of 7 in 3txk

Go back to Chlorine Binding Sites List in 3txk
Chlorine binding site 4 out of 7 in the Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1134

b:56.2
occ:1.00
 CE2 A:PHE38 3.2 39.6 1.0
CZ A:PHE38 3.7 39.8 1.0
CD A:ARG5 3.7 50.4 1.0
CB A:ARG5 3.8 43.0 1.0
CD A:LYS33 4.1 37.5 1.0
CG A:ARG5 4.1 47.3 1.0
NZ A:LYS33 4.1 41.5 1.0
CZ3 A:TRP123 4.2 41.7 1.0
CD2 A:PHE38 4.3 38.5 1.0
CE A:LYS33 4.6 39.0 1.0
CE3 A:TRP123 4.7 40.0 1.0
N A:ARG5 4.7 44.0 1.0
CA A:ARG5 4.8 42.8 1.0
NE A:ARG5 5.0 54.6 1.0

Chlorine binding site 5 out of 7 in 3txk

Go back to Chlorine Binding Sites List in 3txk
Chlorine binding site 5 out of 7 in the Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1135

b:62.8
occ:1.00
 ND2 A:ASN74 2.7 41.2 1.0
C A:ILE78 3.6 38.8 1.0
CA A:ILE78 3.7 38.8 1.0
N A:ILE78 3.7 38.5 1.0
C A:ASN77 3.8 40.2 1.0
N A:PRO79 3.8 39.2 1.0
O A:ILE78 3.9 38.8 1.0
O A:ASN77 4.0 41.1 1.0
CG A:ASN74 4.0 41.3 1.0
CD A:PRO79 4.1 40.4 1.0
CB A:ASN65 4.3 41.4 1.0
CA A:ASN77 4.5 40.9 1.0
OD1 A:ASN74 4.5 40.5 1.0
ND2 A:ASN65 4.6 42.5 1.0
CA A:PRO79 4.6 38.6 1.0
CG A:ASN65 4.9 42.9 1.0

Chlorine binding site 6 out of 7 in 3txk

Go back to Chlorine Binding Sites List in 3txk
Chlorine binding site 6 out of 7 in the Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1136

b:70.0
occ:1.00
 NE A:ARG73 2.9 46.5 1.0
NH2 A:ARG73 3.1 49.2 1.0
CZ A:ARG73 3.4 48.5 1.0
CD A:ARG73 4.1 45.9 1.0
CD2 A:LEU75 4.5 39.7 1.0
NH1 A:ARG73 4.8 49.3 1.0

Chlorine binding site 7 out of 7 in 3txk

Go back to Chlorine Binding Sites List in 3txk
Chlorine binding site 7 out of 7 in the Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Hewl Co-Crystallization with Cisplatin in Dmso Media with Paratone As the Cryoprotectant at pH 6.5 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1137

b:55.5
occ:1.00
 C2 A:DMS130 3.0 0.7 1.0
CB A:ARG68 3.5 47.1 1.0
CG A:ARG68 3.6 51.2 1.0
CD A:ARG68 3.8 52.7 1.0
S A:DMS130 4.1 0.5 1.0
NH1 A:ARG45 4.3 53.4 1.0
O A:DMS130 4.3 0.4 1.0
NH2 A:ARG45 4.5 56.7 1.0
CZ A:ARG45 4.5 55.2 1.0
O A:ARG68 4.7 44.5 1.0
CA A:ARG68 4.9 46.3 1.0

Reference:

S.W.Tanley, A.M.Schreurs, J.R.Helliwell, L.M.Kroon-Batenburg. Experience with Exchange and Archiving of Raw Data: Comparison of Data From Two Diffractometers and Four Software Packages on A Series of Lysozyme Crystals. J.Appl.Crystallogr. V. 46 108 2013.
ISSN: ISSN 0021-8898
PubMed: 23396873
DOI: 10.1107/S0021889812044172
Page generated: Sun Jul 21 05:42:02 2024

Last articles

Zn in 9JPJ
Zn in 9JP7
Zn in 9JPK
Zn in 9JPL
Zn in 9GN6
Zn in 9GN7
Zn in 9GKU
Zn in 9GKW
Zn in 9GKX
Zn in 9GL0
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy