Chlorine in PDB 3u7y: Structure of NIH45-46 Fab in Complex with GP120 of 93TH057 Hiv

The structure of Structure of NIH45-46 Fab in Complex with GP120 of 93TH057 Hiv, PDB code: 3u7y was solved by R.Diskin, P.J.Bjorkman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.05 / 2.45
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	69.130, 70.500, 217.740, 90.00, 90.00, 90.00
R / Rfree (%)	20.7 / 25.6

The binding sites of Chlorine atom in the Structure of NIH45-46 Fab in Complex with GP120 of 93TH057 Hiv (pdb code 3u7y). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of NIH45-46 Fab in Complex with GP120 of 93TH057 Hiv, PDB code: 3u7y:

Chlorine binding site 1 out of 1 in the Structure of NIH45-46 Fab in Complex with GP120 of 93TH057 Hiv


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of NIH45-46 Fab in Complex with GP120 of 93TH057 Hiv within 5.0Å range: probe atom residue distance (Å) B Occ G:Cl504 b:55.7 occ:1.00 ND2 G:ASN279 3.2 64.1 1.0 N H:ASN101 3.2 56.8 1.0 CE G:LYS282 3.3 60.5 1.0 NZ G:LYS282 3.4 57.9 1.0 CA H:TYR100 3.7 66.6 1.0 CE1 H:TYR99D 3.7 59.9 1.0 CD2 H:TYR100 3.8 72.4 1.0 OD1 G:ASN279 3.8 59.8 1.0 CG G:ASN279 3.9 60.6 1.0 CB G:ALA281 3.9 53.7 1.0 CD G:LYS282 3.9 62.5 1.0 C H:TYR100 4.0 61.9 1.0 CB H:ASN101 4.0 47.4 1.0 CD1 H:TYR99D 4.0 59.5 1.0 NE1 H:TRP102 4.1 60.3 1.0 CD1 H:TRP102 4.2 64.2 1.0 CA H:ASN101 4.2 54.2 1.0 CE2 H:TYR100 4.3 72.5 1.0 CG G:LYS282 4.4 64.4 1.0 O H:TYR99D 4.4 67.4 1.0 CG H:TYR100 4.4 70.9 1.0 C G:ALA281 4.6 59.5 1.0 CB H:TYR100 4.6 68.3 1.0 N H:TYR100 4.6 67.8 1.0 O G:ALA281 4.7 59.7 1.0 CA G:ALA281 4.8 55.1 1.0 C H:TYR99D 4.8 67.1 1.0 CZ H:TYR99D 4.9 62.7 1.0 N G:LYS282 5.0 61.5 1.0

R.Diskin, J.F.Scheid, P.M.Marcovecchio, A.P.West, F.Klein, H.Gao, P.N.Gnanapragasam, A.Abadir, M.S.Seaman, M.C.Nussenzweig, P.J.Bjorkman. Increasing the Potency and Breadth of An Hiv Antibody By Using Structure-Based Rational Design. Science V. 334 1289 2011.
ISSN: ISSN 0036-8075
PubMed: 22033520
DOI: 10.1126/SCIENCE.1213782