Atomistry » Chlorine » PDB 3u69-3ue4 » 3u87
Atomistry »
  Chlorine »
    PDB 3u69-3ue4 »
      3u87 »

Chlorine in PDB 3u87: Structure of A Chimeric Construct of Human CK2ALPHA and Human CK2ALPHA' in Complex with A Non-Hydrolysable Atp-Analogue

Enzymatic activity of Structure of A Chimeric Construct of Human CK2ALPHA and Human CK2ALPHA' in Complex with A Non-Hydrolysable Atp-Analogue

All present enzymatic activity of Structure of A Chimeric Construct of Human CK2ALPHA and Human CK2ALPHA' in Complex with A Non-Hydrolysable Atp-Analogue:
2.7.11.1;

Protein crystallography data

The structure of Structure of A Chimeric Construct of Human CK2ALPHA and Human CK2ALPHA' in Complex with A Non-Hydrolysable Atp-Analogue, PDB code: 3u87 was solved by K.Niefind, J.Raaf, O.-G.Issinger, B.Olsen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 36.66 / 2.90
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 127.821, 127.821, 125.333, 90.00, 90.00, 90.00
R / Rfree (%) 18.6 / 21.8

Other elements in 3u87:

The structure of Structure of A Chimeric Construct of Human CK2ALPHA and Human CK2ALPHA' in Complex with A Non-Hydrolysable Atp-Analogue also contains other interesting chemical elements:

Magnesium (Mg) 4 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Structure of A Chimeric Construct of Human CK2ALPHA and Human CK2ALPHA' in Complex with A Non-Hydrolysable Atp-Analogue (pdb code 3u87). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of A Chimeric Construct of Human CK2ALPHA and Human CK2ALPHA' in Complex with A Non-Hydrolysable Atp-Analogue, PDB code: 3u87:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 3u87

Go back to Chlorine Binding Sites List in 3u87
Chlorine binding site 1 out of 2 in the Structure of A Chimeric Construct of Human CK2ALPHA and Human CK2ALPHA' in Complex with A Non-Hydrolysable Atp-Analogue


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of A Chimeric Construct of Human CK2ALPHA and Human CK2ALPHA' in Complex with A Non-Hydrolysable Atp-Analogue within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl404

b:83.5
occ:1.00
NZ A:LYS279 3.2 71.4 1.0
CE A:LYS279 3.6 73.2 1.0
ND1 A:HIS276 3.7 94.1 1.0
OG A:SER277 4.1 84.4 1.0
N A:SER277 4.2 81.1 1.0
CA A:HIS276 4.4 85.2 1.0
CB A:HIS276 4.4 85.5 1.0
CG A:HIS276 4.5 91.0 1.0
CE1 A:HIS276 4.7 96.0 1.0
C A:HIS276 4.8 81.0 1.0
O A:ARG275 5.0 92.8 1.0

Chlorine binding site 2 out of 2 in 3u87

Go back to Chlorine Binding Sites List in 3u87
Chlorine binding site 2 out of 2 in the Structure of A Chimeric Construct of Human CK2ALPHA and Human CK2ALPHA' in Complex with A Non-Hydrolysable Atp-Analogue


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of A Chimeric Construct of Human CK2ALPHA and Human CK2ALPHA' in Complex with A Non-Hydrolysable Atp-Analogue within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl404

b:85.2
occ:1.00
NZ B:LYS279 3.5 71.5 1.0
CE B:LYS279 3.9 72.9 1.0
CD2 B:HIS276 3.9 92.3 1.0
N B:SER277 4.1 80.6 1.0
OG B:SER277 4.1 84.0 1.0
CA B:HIS276 4.2 84.8 1.0
CB B:HIS276 4.4 85.6 1.0
CG B:HIS276 4.5 91.0 1.0
O B:ARG275 4.6 93.0 1.0
C B:HIS276 4.7 80.7 1.0
CB B:SER277 4.9 82.7 1.0

Reference:

K.Klopffleisch, O.G.Issinger, K.Niefind. Low-Density Crystal Packing of Human Protein Kinase CK2 Catalytic Subunit in Complex with Resorufin or Other Ligands: A Tool to Study the Unique Hinge-Region Plasticity of the Enzyme Without Packing Bias. Acta Crystallogr.,Sect.D V. 68 883 2012.
ISSN: ISSN 0907-4449
PubMed: 22868753
DOI: 10.1107/S0907444912016587
Page generated: Sat Dec 12 10:14:09 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy