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Chlorine in PDB 3u8b: Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism
Enzymatic activity of Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism
All present enzymatic activity of Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism:
3.1.1.4;
3.1.1.4;
Protein crystallography data
The structure of Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism, PDB code: 3u8b
was solved by
L.K.Lee,
K.J.Bryant,
R.Bouveret,
P.-W.Lei,
A.P.Duff,
S.J.Harrop,
E.P.Huang,
R.P.Harvey,
M.H.Gelb,
P.P.Gray,
P.M.Curmi,
A.M.Cunningham,
W.B.Church,
K.F.Scott,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 24.45 / 2.30 |
| Space group | P 61 2 2 |
| Cell size a, b, c (Å), α, β, γ (°) | 74.683, 74.683, 89.159, 90.00, 90.00, 120.00 |
| R / Rfree (%) | 20.7 / 25.7 |
Other elements in 3u8b:
The structure of Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism also contains other interesting chemical elements:
| Calcium | (Ca) | 2 atoms |
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism
(pdb code 3u8b). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism, PDB code: 3u8b:
Jump to Chlorine binding site number: 1; 2;
In total 2 binding sites of Chlorine where determined in the Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism, PDB code: 3u8b:
Jump to Chlorine binding site number: 1; 2;
Chlorine binding site 1 out of 2 in 3u8b
Go back to
Chlorine Binding Sites List in 3u8b
Chlorine binding site 1 out
of 2 in the Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 1 of Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism within 5.0Å range:
|
Chlorine binding site 2 out of 2 in 3u8b
Go back to
Chlorine Binding Sites List in 3u8b
Chlorine binding site 2 out
of 2 in the Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Chlorine with other atoms in the Cl binding
site number 2 of Functionally Selective Inhibition of Group Iia Phospholipase A2 Reveals A Role For Vimentin in Regulating Arachidonic Acid Metabolism within 5.0Å range:
|
Reference:
L.K.Lee,
K.J.Bryant,
R.Bouveret,
P.W.Lei,
A.P.Duff,
S.J.Harrop,
E.P.Huang,
R.P.Harvey,
M.H.Gelb,
P.P.Gray,
P.M.Curmi,
A.M.Cunningham,
W.B.Church,
K.F.Scott.
Selective Inhibition of Human Group Iia-Secreted Phospholipase A2 (Hgiia) Signaling Reveals Arachidonic Acid Metabolism Is Associated with Colocalization of Hgiia to Vimentin in Rheumatoid Synoviocytes. J.Biol.Chem. V. 288 15269 2013.
ISSN: ISSN 0021-9258
PubMed: 23482564
DOI: 10.1074/JBC.M112.397893
Page generated: Sat Dec 12 10:14:10 2020
ISSN: ISSN 0021-9258
PubMed: 23482564
DOI: 10.1074/JBC.M112.397893
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