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Atomistry » Chlorine » PDB 3u69-3ue4 » 3u8w » |
Chlorine in PDB 3u8w: Crystal Structure of P38A Mitogen-Activated Protein Kinase in Complex with A Triazolopyridazinone InhibitorEnzymatic activity of Crystal Structure of P38A Mitogen-Activated Protein Kinase in Complex with A Triazolopyridazinone Inhibitor
All present enzymatic activity of Crystal Structure of P38A Mitogen-Activated Protein Kinase in Complex with A Triazolopyridazinone Inhibitor:
2.7.11.24; Protein crystallography data
The structure of Crystal Structure of P38A Mitogen-Activated Protein Kinase in Complex with A Triazolopyridazinone Inhibitor, PDB code: 3u8w
was solved by
C.Mohr,
S.Jordan,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3u8w:
The structure of Crystal Structure of P38A Mitogen-Activated Protein Kinase in Complex with A Triazolopyridazinone Inhibitor also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of P38A Mitogen-Activated Protein Kinase in Complex with A Triazolopyridazinone Inhibitor
(pdb code 3u8w). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of P38A Mitogen-Activated Protein Kinase in Complex with A Triazolopyridazinone Inhibitor, PDB code: 3u8w: Chlorine binding site 1 out of 1 in 3u8wGo back to Chlorine Binding Sites List in 3u8w
Chlorine binding site 1 out
of 1 in the Crystal Structure of P38A Mitogen-Activated Protein Kinase in Complex with A Triazolopyridazinone Inhibitor
Mono view Stereo pair view
Reference:
B.Herberich,
C.Jackson,
R.P.Wurz,
L.H.Pettus,
L.Sherman,
Q.Liu,
B.Henkle,
C.J.Saris,
L.M.Wong,
S.Chmait,
M.R.Lee,
C.Mohr,
F.Hsieh,
A.S.Tasker.
Identification of Triazolopyridazinones As Potent P38ALPHA Inhibitors. Bioorg.Med.Chem.Lett. V. 22 1226 2012.
Page generated: Sat Dec 12 10:14:15 2020
ISSN: ISSN 0960-894X PubMed: 22196117 DOI: 10.1016/J.BMCL.2011.11.067 |
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