Chlorine in PDB 3ub5: Profilin:Actin with A Wide Open Nucleotide Cleft

The structure of Profilin:Actin with A Wide Open Nucleotide Cleft, PDB code: 3ub5 was solved by J.C.Porta, G.E.Borgstahl, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	37.24 / 2.20
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	38.000, 72.000, 186.800, 90.00, 90.00, 90.00
R / Rfree (%)	21.5 / 29

The structure of Profilin:Actin with A Wide Open Nucleotide Cleft also contains other interesting chemical elements:

Calcium

(Ca)

2 atoms

The binding sites of Chlorine atom in the Profilin:Actin with A Wide Open Nucleotide Cleft (pdb code 3ub5). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Profilin:Actin with A Wide Open Nucleotide Cleft, PDB code: 3ub5:

Chlorine binding site 1 out of 1 in the Profilin:Actin with A Wide Open Nucleotide Cleft


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Profilin:Actin with A Wide Open Nucleotide Cleft within 5.0Å range: probe atom residue distance (Å) B Occ P:Cl141 b:44.2 occ:0.70 NH2 P:ARG135 1.7 44.4 1.0 CZ P:ARG135 2.8 36.2 1.0 O P:TYR128 3.0 22.7 1.0 NH1 P:ARG135 3.1 32.2 1.0 OG P:SER132 3.5 31.9 1.0 N P:SER132 3.5 27.9 1.0 CD1 P:TYR128 3.6 25.5 1.0 CB P:ALA131 3.6 23.4 1.0 CE1 P:TYR128 3.7 21.9 1.0 CG P:TYR128 3.7 24.1 1.0 CZ P:TYR128 3.8 20.7 1.0 OG1 P:THR103 3.8 25.8 1.0 CD2 P:PHE83 3.9 18.3 1.0 CE2 P:TYR128 3.9 22.1 1.0 CD2 P:TYR128 3.9 22.2 1.0 CA P:SER132 3.9 30.0 1.0 NE P:ARG135 3.9 44.7 1.0 C P:TYR128 4.0 26.3 1.0 C P:ALA131 4.1 26.1 1.0 CB P:SER132 4.2 27.6 1.0 CA P:TYR128 4.2 27.0 1.0 CA P:ALA131 4.4 25.1 1.0 CG P:PHE83 4.5 17.7 1.0 OH P:TYR128 4.5 21.1 1.0 CB P:TYR128 4.5 25.1 1.0 CB P:PHE83 4.5 17.6 1.0 CE2 P:PHE83 4.6 19.6 1.0 O P:ALA131 4.8 29.0 1.0

J.C.Porta, G.E.Borgstahl. Structural Basis For Profilin-Mediated Actin Nucleotide Exchange. J.Mol.Biol. V. 418 103 2012.
ISSN: ISSN 0022-2836
PubMed: 22366544
DOI: 10.1016/J.JMB.2012.02.012