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Atomistry » Chlorine » PDB 3ue5-3unf » 3um8 » |
Chlorine in PDB 3um8: Wild-Type Plasmodium Falciparum Dhfr-Ts Complexed with Cycloguanil and NadphEnzymatic activity of Wild-Type Plasmodium Falciparum Dhfr-Ts Complexed with Cycloguanil and Nadph
All present enzymatic activity of Wild-Type Plasmodium Falciparum Dhfr-Ts Complexed with Cycloguanil and Nadph:
1.5.1.3; 2.1.1.45; Protein crystallography data
The structure of Wild-Type Plasmodium Falciparum Dhfr-Ts Complexed with Cycloguanil and Nadph, PDB code: 3um8
was solved by
J.Vanichtanankul,
P.Chitnumsub,
S.Kamchonwongpaisan,
Y.Yuthavong,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Wild-Type Plasmodium Falciparum Dhfr-Ts Complexed with Cycloguanil and Nadph
(pdb code 3um8). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Wild-Type Plasmodium Falciparum Dhfr-Ts Complexed with Cycloguanil and Nadph, PDB code: 3um8: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 3um8Go back to Chlorine Binding Sites List in 3um8
Chlorine binding site 1 out
of 2 in the Wild-Type Plasmodium Falciparum Dhfr-Ts Complexed with Cycloguanil and Nadph
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 3um8Go back to Chlorine Binding Sites List in 3um8
Chlorine binding site 2 out
of 2 in the Wild-Type Plasmodium Falciparum Dhfr-Ts Complexed with Cycloguanil and Nadph
Mono view Stereo pair view
Reference:
J.Vanichtanankul,
S.Taweechai,
C.Uttamapinant,
P.Chitnumsub,
T.Vilaivan,
Y.Yuthavong,
S.Kamchonwongpaisan.
Combined Spatial Limitation Around Residues 16 and 108 of Plasmodium Falciparum Dihydrofolate Reductase Explains Resistance to Cycloguanil. Antimicrob.Agents Chemother. V. 56 3928 2012.
Page generated: Sun Jul 21 06:13:06 2024
ISSN: ISSN 0066-4804 PubMed: 22526319 DOI: 10.1128/AAC.00301-12 |
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