Chlorine in PDB 3umr: Crystal Structure of the G202D Mutant of Human G-Alpha-I1

The structure of Crystal Structure of the G202D Mutant of Human G-Alpha-I1, PDB code: 3umr was solved by C.A.Johnston, K.Afshar, J.T.Snyder, G.G.Tall, P.Gonczy, D.P.Siderovski, F.S.Willard, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	23.92 / 2.04
Space group	I 4
Cell size a, b, c (Å), α, β, γ (°)	121.952, 121.952, 67.382, 90.00, 90.00, 90.00
R / Rfree (%)	17 / 21

The binding sites of Chlorine atom in the Crystal Structure of the G202D Mutant of Human G-Alpha-I1 (pdb code 3umr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of the G202D Mutant of Human G-Alpha-I1, PDB code: 3umr:
Jump to Chlorine binding site number: 1; 2; 3;

Chlorine binding site 1 out of 3 in the Crystal Structure of the G202D Mutant of Human G-Alpha-I1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the G202D Mutant of Human G-Alpha-I1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl356 b:87.0 occ:1.00 ND2 A:ASN331 3.4 38.9 1.0 O A:HOH368 3.6 49.6 1.0 CA A:ASN331 3.8 30.2 1.0 O A:HOH507 3.9 47.9 1.0 CB A:ASN331 4.1 30.4 1.0 CG A:ASN331 4.3 31.0 1.0 N A:ASN331 4.4 30.6 1.0 CB A:PHE334 4.5 31.1 1.0 O A:LYS330 4.5 34.0 1.0 CG A:PHE334 4.7 41.7 1.0 C A:LYS330 4.7 33.5 1.0 CD2 A:PHE334 4.8 41.5 1.0 C A:ASN331 4.9 34.3 1.0 O A:ASN331 5.0 29.5 1.0

Chlorine binding site 2 out of 3 in the Crystal Structure of the G202D Mutant of Human G-Alpha-I1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the G202D Mutant of Human G-Alpha-I1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl357 b:81.7 occ:1.00 O A:HOH533 3.4 43.6 1.0 N A:ALA121 3.6 36.0 1.0 CB A:THR120 3.9 43.2 1.0 CA A:THR120 3.9 37.7 1.0 C A:THR120 4.3 38.1 1.0 CB A:ALA121 4.3 40.5 1.0 CG2 A:THR120 4.3 42.0 1.0 CA A:ALA121 4.6 40.0 1.0

Chlorine binding site 3 out of 3 in the Crystal Structure of the G202D Mutant of Human G-Alpha-I1


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of the G202D Mutant of Human G-Alpha-I1 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl358 b:95.5 occ:1.00 O A:ILE93 4.0 48.7 1.0 CE2 A:PHE95 4.0 39.5 1.0 O A:HOH512 4.3 56.9 1.0 N A:GLY89 4.4 48.3 1.0 CA A:GLY89 4.5 46.6 1.0 CD2 A:PHE95 4.5 45.6 1.0 CB A:MET88 4.5 36.5 1.0 CZ A:PHE95 4.6 40.4 1.0 C A:MET88 4.6 40.5 1.0 O A:MET88 4.7 42.5 1.0

C.A.Johnston, K.Afshar, J.T.Snyder, G.G.Tall, P.Gonczy, D.P.Siderovski, F.S.Willard. Structural Determinants Underlying the Temperature-Sensitive Nature of A G-Alpha Mutant in Asymmetric Cell Division of Caenorhabditis Elegans To Be Published.