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Atomistry » Chlorine » PDB 3unh-3uwb » 3uol | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 3unh-3uwb » 3uol » |
Chlorine in PDB 3uol: Aurora A in Complex with SO2-162Enzymatic activity of Aurora A in Complex with SO2-162
All present enzymatic activity of Aurora A in Complex with SO2-162:
2.7.11.1; Protein crystallography data
The structure of Aurora A in Complex with SO2-162, PDB code: 3uol
was solved by
M.P.Martin,
J.-Y.Zhu,
E.Schonbrunn,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Aurora A in Complex with SO2-162
(pdb code 3uol). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Aurora A in Complex with SO2-162, PDB code: 3uol: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 3uolGo back to Chlorine Binding Sites List in 3uol
Chlorine binding site 1 out
of 2 in the Aurora A in Complex with SO2-162
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 3uolGo back to Chlorine Binding Sites List in 3uol
Chlorine binding site 2 out
of 2 in the Aurora A in Complex with SO2-162
Mono view Stereo pair view
Reference:
M.P.Martin,
J.Y.Zhu,
H.R.Lawrence,
R.Pireddu,
Y.Luo,
R.Alam,
S.Ozcan,
S.M.Sebti,
N.J.Lawrence,
E.Schonbrunn.
A Novel Mechanism By Which Small Molecule Inhibitors Induce the Dfg Flip in Aurora A. Acs Chem.Biol. V. 7 698 2012.
Page generated: Sat Dec 12 10:15:35 2020
ISSN: ISSN 1554-8929 PubMed: 22248356 DOI: 10.1021/CB200508B |
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