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Chlorine in PDB 3uq0: Crystal Structure of the Post-Catalytic Product Complex of Polymerase Lambda with An Ramp at the Primer Terminus.

Enzymatic activity of Crystal Structure of the Post-Catalytic Product Complex of Polymerase Lambda with An Ramp at the Primer Terminus.

All present enzymatic activity of Crystal Structure of the Post-Catalytic Product Complex of Polymerase Lambda with An Ramp at the Primer Terminus.:
2.7.7.7;

Protein crystallography data

The structure of Crystal Structure of the Post-Catalytic Product Complex of Polymerase Lambda with An Ramp at the Primer Terminus., PDB code: 3uq0 was solved by R.A.Gosavi, A.F.Moon, T.A.Kunkel, L.C.Pedersen, K.Bebenek, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 25.92 / 2.14
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 55.843, 64.241, 139.290, 90.00, 90.00, 90.00
R / Rfree (%) 19.5 / 23.9

Other elements in 3uq0:

The structure of Crystal Structure of the Post-Catalytic Product Complex of Polymerase Lambda with An Ramp at the Primer Terminus. also contains other interesting chemical elements:

Sodium (Na) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of the Post-Catalytic Product Complex of Polymerase Lambda with An Ramp at the Primer Terminus. (pdb code 3uq0). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the Post-Catalytic Product Complex of Polymerase Lambda with An Ramp at the Primer Terminus., PDB code: 3uq0:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 3uq0

Go back to Chlorine Binding Sites List in 3uq0
Chlorine binding site 1 out of 2 in the Crystal Structure of the Post-Catalytic Product Complex of Polymerase Lambda with An Ramp at the Primer Terminus.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Post-Catalytic Product Complex of Polymerase Lambda with An Ramp at the Primer Terminus. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl5

b:70.2
occ:1.00
O A:HOH198 3.7 38.4 1.0
NH2 A:ARG419 3.7 30.3 1.0
O A:HOH604 3.8 49.2 1.0
NE A:ARG419 3.9 33.0 1.0
CZ A:ARG419 4.2 32.2 1.0
CG A:PRO570 4.2 29.5 1.0
CD A:PRO570 4.6 29.8 1.0
O A:HOH599 4.8 53.5 1.0
CG A:ARG419 5.0 30.9 1.0

Chlorine binding site 2 out of 2 in 3uq0

Go back to Chlorine Binding Sites List in 3uq0
Chlorine binding site 2 out of 2 in the Crystal Structure of the Post-Catalytic Product Complex of Polymerase Lambda with An Ramp at the Primer Terminus.


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Post-Catalytic Product Complex of Polymerase Lambda with An Ramp at the Primer Terminus. within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl6

b:79.0
occ:1.00
NH2 A:ARG275 3.9 61.6 1.0
NH1 A:ARG275 4.2 60.1 1.0
CZ A:ARG275 4.5 66.0 1.0

Reference:

R.A.Gosavi, A.F.Moon, T.A.Kunkel, L.C.Pedersen, K.Bebenek. The Catalytic Cycle For Ribonucleotide Incorporation By Human Dna Pol Lambda Nucleic Acids Res. V. 40 7518 2012.
ISSN: ISSN 0305-1048
PubMed: 22584622
DOI: 10.1093/NAR/GKS413
Page generated: Sat Dec 12 10:15:44 2020

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