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Atomistry » Chlorine » PDB 3zh8-3zoj » 3zno | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 3zh8-3zoj » 3zno » |
Chlorine in PDB 3zno: In Vitro and in Vivo Inhibition of Human D-Amino Acid Oxidase: Regulation of D-Serine Concentration in the BrainEnzymatic activity of In Vitro and in Vivo Inhibition of Human D-Amino Acid Oxidase: Regulation of D-Serine Concentration in the Brain
All present enzymatic activity of In Vitro and in Vivo Inhibition of Human D-Amino Acid Oxidase: Regulation of D-Serine Concentration in the Brain:
1.4.3.3; Protein crystallography data
The structure of In Vitro and in Vivo Inhibition of Human D-Amino Acid Oxidase: Regulation of D-Serine Concentration in the Brain, PDB code: 3zno
was solved by
S.C.Hopkins,
M.L.R.Heffernan,
L.D.Saraswat,
C.A.Bowen,
L.Melnick,
L.W.Hardy,
M.A.Orsini,
M.S.Allen,
P.Koch,
K.L.Spear,
R.J.Foglesong,
M.Soukri,
M.Chytil,
Q.K.Fang,
S.W.Jones,
M.A.Varney,
A.Panatier,
S.H.R.Oliet,
L.Pollegioni,
L.Piubelli,
G.Molla,
M.Nardini,
T.H.Large,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the In Vitro and in Vivo Inhibition of Human D-Amino Acid Oxidase: Regulation of D-Serine Concentration in the Brain
(pdb code 3zno). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the In Vitro and in Vivo Inhibition of Human D-Amino Acid Oxidase: Regulation of D-Serine Concentration in the Brain, PDB code: 3zno: Jump to Chlorine binding site number: 1; 2; Chlorine binding site 1 out of 2 in 3znoGo back to Chlorine Binding Sites List in 3zno
Chlorine binding site 1 out
of 2 in the In Vitro and in Vivo Inhibition of Human D-Amino Acid Oxidase: Regulation of D-Serine Concentration in the Brain
Mono view Stereo pair view
Chlorine binding site 2 out of 2 in 3znoGo back to Chlorine Binding Sites List in 3zno
Chlorine binding site 2 out
of 2 in the In Vitro and in Vivo Inhibition of Human D-Amino Acid Oxidase: Regulation of D-Serine Concentration in the Brain
Mono view Stereo pair view
Reference:
S.C.Hopkins,
M.L.R.Heffernan,
L.D.Saraswat,
C.A.Bowen,
L.Melnick,
L.W.Hardy,
M.A.Orsini,
M.S.Allen,
P.Koch,
K.L.Spear,
R.J.Foglesong,
M.Soukri,
M.Chytil,
Q.K.Fang,
S.W.Jones,
M.A.Varney,
A.Panatier,
S.H.R.Oliet,
L.Pollegioni,
L.Piubelli,
G.Molla,
M.Nardini,
T.H.Large.
Structural, Kinetic, and Pharmacodynamic Mechanisms of D- Amino Acid Oxidase Inhibition By Small Molecules. J.Med.Chem. V. 56 3710 2013.
Page generated: Sun Jul 21 08:12:12 2024
ISSN: ISSN 0022-2623 PubMed: 23631755 DOI: 10.1021/JM4002583 |
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