Chlorine in PDB 3zot: Structure of E.Coli Rhomboid Protease Glpg in Complex with Monobactam L29 (Data Set 2)

All present enzymatic activity of Structure of E.Coli Rhomboid Protease Glpg in Complex with Monobactam L29 (Data Set 2):
3.4.21.105;

The structure of Structure of E.Coli Rhomboid Protease Glpg in Complex with Monobactam L29 (Data Set 2), PDB code: 3zot was solved by K.R.Vinothkumar, O.A.Pierrat, J.M.Large, M.Freeman, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	53.38 / 2.40
Space group	H 3 2
Cell size a, b, c (Å), α, β, γ (°)	110.200, 110.200, 128.900, 90.00, 90.00, 120.00
R / Rfree (%)	19.8 / 25.2

The binding sites of Chlorine atom in the Structure of E.Coli Rhomboid Protease Glpg in Complex with Monobactam L29 (Data Set 2) (pdb code 3zot). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of E.Coli Rhomboid Protease Glpg in Complex with Monobactam L29 (Data Set 2), PDB code: 3zot:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of E.Coli Rhomboid Protease Glpg in Complex with Monobactam L29 (Data Set 2)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of E.Coli Rhomboid Protease Glpg in Complex with Monobactam L29 (Data Set 2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl411 b:51.0 occ:1.00 NZ A:LYS173 3.0 30.8 1.0 NH1 A:ARG214 3.4 37.6 1.0 NH2 A:ARG214 3.5 53.4 1.0 CE A:LYS173 3.8 30.2 1.0 CZ A:ARG214 3.8 42.9 1.0 OD2 A:ASP268 3.9 30.9 1.0 CG A:ASP268 4.1 35.9 1.0 CB A:ASP268 4.3 35.7 1.0 OH A:TYR210 4.6 34.3 1.0 CD2 A:LEU169 4.6 30.7 1.0 OD1 A:ASP268 4.7 33.7 1.0 O A:ASP268 4.8 43.2 1.0

Chlorine binding site 2 out of 2 in the Structure of E.Coli Rhomboid Protease Glpg in Complex with Monobactam L29 (Data Set 2)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of E.Coli Rhomboid Protease Glpg in Complex with Monobactam L29 (Data Set 2) within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl412 b:50.5 occ:1.00 N A:GLY228 3.3 37.8 1.0 OE1 A:GLN226 3.7 68.1 1.0 N A:ARG227 3.9 40.7 1.0 CB A:ARG227 3.9 44.8 1.0 CA A:ARG227 4.1 42.5 1.0 CA A:GLY228 4.2 36.3 1.0 C A:ARG227 4.2 43.0 1.0 CB A:GLN226 4.3 47.0 1.0 CG A:GLN226 4.3 49.5 1.0 CD A:GLN226 4.4 65.1 1.0 C A:GLN226 4.5 47.4 1.0 CG A:ARG227 5.0 44.0 1.0 CA A:GLN226 5.0 51.4 1.0

K.R.Vinothkumar, O.A.Pierrat, J.M.Large, M.Freeman. Structure of Rhomboid Protease in Complex with Beta-Lactam Inhibitors Defines the S2' Cavity. Structure V. 21 1051 2013.
ISSN: ISSN 0969-2126
PubMed: 23665170
DOI: 10.1016/J.STR.2013.03.013