Atomistry » Chlorine » PDB 3zx3-4a7i » 3zzh
Atomistry »
  Chlorine »
    PDB 3zx3-4a7i »
      3zzh »

Chlorine in PDB 3zzh: Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine

Enzymatic activity of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine

All present enzymatic activity of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine:
2.7.2.8;

Protein crystallography data

The structure of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine, PDB code: 3zzh was solved by S.De Cima, F.Gil-Ortiz, M.Crabeel, I.Fita, V.Rubio, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 20.00 / 2.10
Space group P 21 21 21
Cell size a, b, c (Å), α, β, γ (°) 69.489, 99.596, 189.238, 90.00, 90.00, 90.00
R / Rfree (%) 18.037 / 21.544

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine (pdb code 3zzh). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 5 binding sites of Chlorine where determined in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine, PDB code: 3zzh:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5;

Chlorine binding site 1 out of 5 in 3zzh

Go back to Chlorine Binding Sites List in 3zzh
Chlorine binding site 1 out of 5 in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1359

b:25.9
occ:1.00
 NZ A:LYS283 3.0 16.9 1.0
O A:HOH2120 3.3 6.5 1.0
O A:GLY273 3.5 14.2 1.0
N A:GLY345 3.5 21.6 1.0
CA A:GLY345 4.0 19.7 1.0
C A:GLY273 4.3 13.2 1.0
CA A:GLY273 4.3 14.0 1.0
CE A:LYS283 4.4 17.0 1.0
C A:ALA344 4.5 23.3 1.0
CA A:ALA344 4.6 25.8 1.0
OD2 A:ASP333 4.6 24.2 1.0
CG A:LYS283 4.6 16.4 1.0
O A:LYS272 4.7 15.6 1.0
CB A:ALA344 4.7 26.0 1.0
O A:HOH2123 4.8 2.9 1.0
CD A:LYS283 4.8 16.1 1.0

Chlorine binding site 2 out of 5 in 3zzh

Go back to Chlorine Binding Sites List in 3zzh
Chlorine binding site 2 out of 5 in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1367

b:21.2
occ:1.00
 O B:HOH2040 2.9 4.2 1.0
O B:HOH2142 3.0 11.6 1.0
N B:GLU271 3.4 11.4 1.0
CA B:ASN270 3.6 10.2 1.0
CG B:GLU271 3.7 12.7 1.0
CB B:ASN270 3.8 10.7 1.0
O B:HOH2110 3.9 8.7 1.0
C B:ASN270 4.0 10.7 1.0
CB B:ALA107 4.0 9.8 1.0
CA B:GLY105 4.2 9.3 1.0
CB B:GLU271 4.2 12.7 1.0
CG1 B:ILE108 4.3 9.7 1.0
CA B:GLU271 4.4 12.2 1.0
CD B:GLU271 4.4 14.0 1.0
O B:LEU269 4.5 9.1 1.0
O B:HOH2037 4.6 7.2 1.0
C B:GLY105 4.6 9.0 1.0
CD1 B:ILE108 4.7 10.3 1.0
N B:ALA107 4.7 9.1 1.0
OE1 B:GLU271 4.8 15.7 1.0
N B:ILE108 4.8 9.0 1.0
C2 B:EDO1364 4.8 32.7 1.0
O2 B:EDO1364 4.8 32.9 1.0
CA B:ALA107 4.8 9.4 1.0
O B:GLY105 4.8 8.6 1.0
N B:ASN270 4.8 9.7 1.0
O B:HOH2141 4.9 26.5 1.0
C2 B:EDO1359 4.9 39.3 1.0
O2 B:EDO1359 4.9 39.0 1.0
OE2 B:GLU271 5.0 14.0 1.0

Chlorine binding site 3 out of 5 in 3zzh

Go back to Chlorine Binding Sites List in 3zzh
Chlorine binding site 3 out of 5 in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Cl1360

b:36.9
occ:1.00
 ND2 C:ASN141 3.0 13.8 1.0
CA C:PRO138 3.8 14.1 1.0
CG C:ASN141 4.0 14.0 1.0
CB C:ASN141 4.1 14.2 1.0
CB C:PRO138 4.1 14.5 1.0
CG C:PRO138 4.5 14.5 1.0
N C:PRO138 4.5 13.4 1.0
O C:PRO138 4.6 13.7 1.0
C C:PRO138 4.7 13.7 1.0
O C:GLY137 4.8 13.6 1.0
C C:GLY137 5.0 13.1 1.0

Chlorine binding site 4 out of 5 in 3zzh

Go back to Chlorine Binding Sites List in 3zzh
Chlorine binding site 4 out of 5 in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl1367

b:19.2
occ:1.00
 O D:HOH2137 2.9 16.1 1.0
O D:HOH2030 2.9 3.8 1.0
O D:HOH2106 3.1 21.5 1.0
N D:GLU271 3.4 11.4 1.0
CA D:ASN270 3.6 10.2 1.0
CG D:GLU271 3.7 13.7 1.0
CB D:ASN270 3.8 10.6 1.0
O D:HOH2103 3.9 8.0 1.0
C D:ASN270 3.9 10.5 1.0
CA D:GLY105 4.0 8.9 1.0
CB D:ALA107 4.1 9.9 1.0
CB D:GLU271 4.2 12.7 1.0
O D:HOH2029 4.3 4.7 1.0
CG1 D:ILE108 4.3 8.8 1.0
CA D:GLU271 4.4 12.4 1.0
CD1 D:ILE108 4.4 8.9 1.0
CD D:GLU271 4.5 15.4 1.0
C D:GLY105 4.5 8.8 1.0
O D:LEU269 4.5 9.4 1.0
O D:HOH2138 4.5 30.9 1.0
N D:ALA107 4.7 9.1 1.0
O D:GLY105 4.7 8.8 1.0
N D:ILE108 4.8 8.9 1.0
O D:HOH2101 4.8 18.6 1.0
N D:ASN270 4.8 9.8 1.0
CA D:ALA107 4.9 9.6 1.0
C1 D:EDO1364 4.9 35.5 1.0
OE1 D:GLU271 4.9 17.0 1.0
N D:GLY105 4.9 8.8 1.0

Chlorine binding site 5 out of 5 in 3zzh

Go back to Chlorine Binding Sites List in 3zzh
Chlorine binding site 5 out of 5 in the Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of the Amino Acid Kinase Domain From Saccharomyces Cerevisiae Acetylglutamate Kinase in Complex with Its Feed-Back Inhibitor L-Arginine within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Cl1368

b:29.2
occ:1.00
 O D:HOH2068 3.2 20.2 1.0
NH2 D:ARG169 3.2 14.2 1.0
OG C:SER195 3.2 15.1 1.0
NE D:ARG169 3.5 14.2 1.0
CE D:MET245 3.6 21.8 1.0
CZ D:ARG169 3.8 14.8 1.0
N C:GLY196 3.8 14.9 1.0
CB C:SER195 3.8 15.0 1.0
CA C:GLY196 3.9 14.9 1.0
SD D:MET245 3.9 20.8 1.0
C C:SER195 4.3 14.6 1.0
O D:HOH2079 4.3 15.3 1.0
CB D:ARG169 4.7 11.8 1.0
CD D:ARG169 4.7 13.4 1.0
CA C:SER195 4.7 14.3 1.0
CG D:ARG169 4.8 12.2 1.0
O C:SER195 4.9 14.8 1.0

Reference:

S.De Cima, F.Gil-Ortiz, M.Crabeel, I.Fita, V.Rubio. Insight on An Arginine Synthesis Metabolon From the Tetrameric Structure of Yeast Acetylglutamate Kinase Plos One V. 7 34734 2012.
ISSN: ISSN 1932-6203
PubMed: 22529931
DOI: 10.1371/JOURNAL.PONE.0034734
Page generated: Fri Jul 11 12:36:40 2025

Last articles

Cl in 4LU4
Cl in 4LSQ
Cl in 4LR4
Cl in 4LTK
Cl in 4LTI
Cl in 4LTG
Cl in 4LSU
Cl in 4LSN
Cl in 4LSB
Cl in 4LSL
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy