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Atomistry » Chlorine » PDB 4a7i-4ain » 4aac | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4a7i-4ain » 4aac » |
Chlorine in PDB 4aac: P38ALPHA Map Kinase Bound to Cmpd 29Enzymatic activity of P38ALPHA Map Kinase Bound to Cmpd 29
All present enzymatic activity of P38ALPHA Map Kinase Bound to Cmpd 29:
2.7.11.24; Protein crystallography data
The structure of P38ALPHA Map Kinase Bound to Cmpd 29, PDB code: 4aac
was solved by
S.Gerhardt,
D.Hargreaves,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the P38ALPHA Map Kinase Bound to Cmpd 29
(pdb code 4aac). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the P38ALPHA Map Kinase Bound to Cmpd 29, PDB code: 4aac: Chlorine binding site 1 out of 1 in 4aacGo back to Chlorine Binding Sites List in 4aac
Chlorine binding site 1 out
of 1 in the P38ALPHA Map Kinase Bound to Cmpd 29
Mono view Stereo pair view
Reference:
D.S.Brown,
J.G.Cumming,
P.Bethel,
J.Finlayson,
S.Gerhardt,
I.Nash,
R.Pauptit,
K.G.Pike,
A.Reid,
W.Snelson,
S.Swallow,
C.Thompson.
The Discovery of N-Cyclopropyl-4-Methyl-3-[6--(4-Methylpiperazin-1-Yl-4-Oxoqu Inazolin-3(4H)-Yl]Benzamide (AZD6703), A Clinical P38ALPHA Map Kinase Inhibitor For the Treatment of Inflammatory Diseases Bioorg.Med.Chem.Lett. V. 22 3879 2012.
Page generated: Sat Dec 12 10:23:12 2020
ISSN: ISSN 0960-894X PubMed: 22608965 DOI: 10.1016/J.BMCL.2012.04.116 |
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