Chlorine in PDB 4ap5: Crystal Structure of Human POFUT2

All present enzymatic activity of Crystal Structure of Human POFUT2:
2.4.1.221;

The structure of Crystal Structure of Human POFUT2, PDB code: 4ap5 was solved by C.Chen, J.J.Keusch, D.Klein, D.Hess, J.Hofsteenge, H.Gut, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.657 / 3.00
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	118.628, 118.628, 196.227, 90.00, 90.00, 120.00
R / Rfree (%)	17.35 / 23.59

The structure of Crystal Structure of Human POFUT2 also contains other interesting chemical elements:

Magnesium

(Mg)

1 atom

The binding sites of Chlorine atom in the Crystal Structure of Human POFUT2 (pdb code 4ap5). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human POFUT2, PDB code: 4ap5:

Chlorine binding site 1 out of 1 in the Crystal Structure of Human POFUT2


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human POFUT2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1432 b:48.6 occ:1.00 OE1 A:GLN99 3.0 96.4 1.0 NH2 A:ARG88 3.6 7.0 0.4 N A:GLY365 3.6 32.4 1.0 CB A:ASP364 3.8 54.6 1.0 CZ A:ARG88 4.2 27.5 0.4 CD A:GLN99 4.2 85.3 1.0 CA A:GLY365 4.2 39.6 1.0 CZ A:PHE107 4.3 39.6 1.0 N A:ASP364 4.4 42.4 1.0 CA A:ASP364 4.4 36.1 1.0 C A:ASP364 4.4 33.4 1.0 CE2 A:PHE107 4.5 42.1 1.0 CD1 A:PHE56 4.5 15.4 1.0 NE A:ARG88 4.6 34.9 0.4 NH1 A:ARG88 4.8 18.8 0.4 CD1 A:ILE102 4.8 20.5 1.0 CB A:GLN99 4.8 78.6 1.0 N A:GLY87 4.8 32.4 1.0 CG A:GLN99 4.9 80.3 1.0 CE1 A:PHE56 5.0 19.9 1.0 CB A:TRP86 5.0 18.5 1.0

C.I.Chen, J.J.Keusch, D.Klein, D.Hess, J.Hofsteenge, H.Gut. Structure of Human POFUT2: Insights Into Thrombospondin Type 1 Repeat Fold and O-Fucosylation. Embo J. V. 31 3183 2012.
ISSN: ISSN 0261-4189
PubMed: 22588082
DOI: 10.1038/EMBOJ.2012.143