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Atomistry » Chlorine » PDB 4aqd-4azk » 4aw0 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4aqd-4azk » 4aw0 » |
Chlorine in PDB 4aw0: Human PDK1 Kinase Domain in Complex with Allosteric Compound PS182 Bound to the Pif-PocketEnzymatic activity of Human PDK1 Kinase Domain in Complex with Allosteric Compound PS182 Bound to the Pif-Pocket
All present enzymatic activity of Human PDK1 Kinase Domain in Complex with Allosteric Compound PS182 Bound to the Pif-Pocket:
2.7.11.1; Protein crystallography data
The structure of Human PDK1 Kinase Domain in Complex with Allosteric Compound PS182 Bound to the Pif-Pocket, PDB code: 4aw0
was solved by
J.O.Schulze,
K.Busschots,
L.A.Lopez-Garcia,
C.Lammi,
A.Stroba,
S.Zeuzem,
A.Piiper,
P.M.Alzari,
S.Neimanis,
J.M.Arencibia,
M.Engel,
R.M.Biondi,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4aw0:
The structure of Human PDK1 Kinase Domain in Complex with Allosteric Compound PS182 Bound to the Pif-Pocket also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human PDK1 Kinase Domain in Complex with Allosteric Compound PS182 Bound to the Pif-Pocket
(pdb code 4aw0). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human PDK1 Kinase Domain in Complex with Allosteric Compound PS182 Bound to the Pif-Pocket, PDB code: 4aw0: Chlorine binding site 1 out of 1 in 4aw0Go back to Chlorine Binding Sites List in 4aw0
Chlorine binding site 1 out
of 1 in the Human PDK1 Kinase Domain in Complex with Allosteric Compound PS182 Bound to the Pif-Pocket
Mono view Stereo pair view
Reference:
K.Busschots,
L.A.Lopez-Garcia,
C.Lammi,
A.Stroba,
S.Zeuzem,
A.Piiper,
P.M.Alzari,
S.Neimanis,
J.M.Arencibia,
M.Engel,
J.O.Schulze,
R.M.Biondi.
Substrate-Selective Inhibition of Protein Kinase PDK1 By Small Compounds That Bind to the Pif-Pocket Allosteric Docking Site. Chem.Biol. V. 19 1152 2012.
Page generated: Sat Dec 12 10:24:37 2020
ISSN: ISSN 1074-5521 PubMed: 22999883 DOI: 10.1016/J.CHEMBIOL.2012.07.017 |
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