Chlorine in PDB 4ayc: RNF8 Ring Domain Structure

The structure of RNF8 Ring Domain Structure, PDB code: 4ayc was solved by F.Mattiroli, J.H.A.Vissers, W.J.Van Dijk, P.Ikpa, E.Citterio, W.Vermeulen, J.A.Marteijn, T.K.Sixma, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.29 / 1.90
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	47.374, 213.717, 34.102, 90.00, 90.00, 90.00
R / Rfree (%)	19.973 / 22.948

The structure of RNF8 Ring Domain Structure also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

The binding sites of Chlorine atom in the RNF8 Ring Domain Structure (pdb code 4ayc). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the RNF8 Ring Domain Structure, PDB code: 4ayc:

Chlorine binding site 1 out of 1 in the RNF8 Ring Domain Structure


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of RNF8 Ring Domain Structure within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1489 b:67.9 occ:1.00 N B:ASP443 3.4 49.0 1.0 CG B:ASP443 3.9 55.0 1.0 CB B:ASP443 4.0 49.7 1.0 OD2 B:ASP443 4.0 63.0 1.0 CA B:LYS442 4.0 51.0 1.0 C B:LYS442 4.2 43.7 1.0 CA B:ASP443 4.3 45.7 1.0 OD1 B:ASP443 4.3 55.9 1.0 CB B:LYS442 4.4 49.8 1.0 CG B:LYS442 4.7 55.6 1.0 NZ B:LYS445 5.0 76.6 1.0

F.Mattiroli, J.H.A.Vissers, W.J.Van Dijk, P.Ikpa, E.Citterio, W.Vermeulen, J.A.Marteijn, T.K.Sixma. RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive Dna Damage Signaling Cell(Cambridge,Mass.) V. 150 1182 2012.
ISSN: ISSN 0092-8674
PubMed: 22980979
DOI: 10.1016/J.CELL.2012.08.005