Chlorine in PDB 4azr: Human Epidermal Fatty Acid-Binding Protein (FABP5) in Complex with the Endocannabinoid Anandamide

The structure of Human Epidermal Fatty Acid-Binding Protein (FABP5) in Complex with the Endocannabinoid Anandamide, PDB code: 4azr was solved by B.Sanson, T.Wang, J.Sun, M.Kaczocha, I.Ojima, D.Deutsch, H.Li, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.95
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	66.120, 115.150, 108.350, 90.00, 90.00, 90.00
R / Rfree (%)	21.907 / 26.798

The binding sites of Chlorine atom in the Human Epidermal Fatty Acid-Binding Protein (FABP5) in Complex with the Endocannabinoid Anandamide (pdb code 4azr). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Epidermal Fatty Acid-Binding Protein (FABP5) in Complex with the Endocannabinoid Anandamide, PDB code: 4azr:

Chlorine binding site 1 out of 1 in the Human Epidermal Fatty Acid-Binding Protein (FABP5) in Complex with the Endocannabinoid Anandamide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Epidermal Fatty Acid-Binding Protein (FABP5) in Complex with the Endocannabinoid Anandamide within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1136 b:24.0 occ:1.00 OG B:SER16 3.2 24.6 1.0 O B:HOH2002 3.2 27.6 1.0 N B:PHE19 3.4 24.9 1.0 CB B:PHE19 3.6 23.7 1.0 O B:SER16 3.8 29.4 1.0 N B:ASP20 4.0 29.7 1.0 CA B:PHE19 4.0 24.0 1.0 N B:GLY18 4.0 26.7 1.0 CB B:SER16 4.1 24.8 1.0 C B:SER16 4.3 26.5 1.0 C B:GLY18 4.4 24.9 1.0 C B:PHE19 4.4 26.1 1.0 C B:LYS17 4.5 25.2 1.0 CA B:GLY18 4.6 26.0 1.0 CA B:LYS17 4.7 26.5 1.0 N B:LYS17 4.8 25.1 1.0 CA B:SER16 4.9 25.1 1.0 CB B:ASP20 4.9 36.9 1.0 CG B:PHE19 4.9 21.7 1.0

B.Sanson, T.Wang, J.Sun, L.Wang, M.Kaczocha, I.Ojima, D.Deutsch, H.Li. Crystallographic Study of FABP5 As An Intracellular Endocannabinoid Transporter. Acta Crystallogr.,Sect.D V. 70 290 2014.
ISSN: ISSN 0907-4449
PubMed: 24531463
DOI: 10.1107/S1399004713026795