Chlorine in PDB 4b36: Crystal Structure of Human Angiogenin with An Engineered Loop Exhibits Conformational Flexibility at the Functional Regions of the Molecule

The structure of Crystal Structure of Human Angiogenin with An Engineered Loop Exhibits Conformational Flexibility at the Functional Regions of the Molecule, PDB code: 4b36 was solved by N.Thiyagarajan, K.R.Acharya, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.151 / 1.76
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	38.353, 54.676, 94.731, 90.00, 90.00, 90.00
R / Rfree (%)	23.65 / 28.53

The binding sites of Chlorine atom in the Crystal Structure of Human Angiogenin with An Engineered Loop Exhibits Conformational Flexibility at the Functional Regions of the Molecule (pdb code 4b36). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human Angiogenin with An Engineered Loop Exhibits Conformational Flexibility at the Functional Regions of the Molecule, PDB code: 4b36:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Human Angiogenin with An Engineered Loop Exhibits Conformational Flexibility at the Functional Regions of the Molecule


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Angiogenin with An Engineered Loop Exhibits Conformational Flexibility at the Functional Regions of the Molecule within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1125 b:24.9 occ:1.00 NE B:ARG33 3.2 22.6 1.0 NH2 B:ARG32 3.4 33.7 1.0 NE B:ARG32 3.5 32.0 1.0 NH2 B:ARG33 3.7 24.3 1.0 CZ B:ARG32 3.9 26.3 1.0 CZ B:ARG33 3.9 25.0 1.0 CD1 B:ILE29 4.1 26.8 1.0 CB B:ARG32 4.1 25.6 1.0 CD B:ARG33 4.2 22.1 1.0 CG B:ARG32 4.6 27.8 1.0 CD B:ARG32 4.7 30.3 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Human Angiogenin with An Engineered Loop Exhibits Conformational Flexibility at the Functional Regions of the Molecule


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human Angiogenin with An Engineered Loop Exhibits Conformational Flexibility at the Functional Regions of the Molecule within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1126 b:32.0 occ:1.00 O B:HOH2044 3.2 41.1 1.0 N B:THR44 3.2 24.4 1.0 NH2 B:ARG123 3.3 38.8 1.0 NH1 B:ARG123 3.6 37.4 1.0 CE1 B:HIS13 3.6 27.4 1.0 CA B:ASN43 3.7 27.1 1.0 CD1 B:LEU117 3.8 27.9 1.0 OG1 B:THR44 3.9 30.3 1.0 C B:ASN43 3.9 25.5 1.0 CB B:THR44 3.9 30.3 1.0 CZ B:ARG123 3.9 38.4 1.0 O B:HOH2020 4.0 45.8 1.0 OD1 B:ASN43 4.0 28.9 1.0 ND1 B:HIS13 4.1 24.1 1.0 CA B:THR44 4.1 23.3 1.0 O B:ILE42 4.3 27.1 1.0 CG B:ASN43 4.4 27.6 1.0 N B:ASN43 4.5 28.0 1.0 NZ B:LYS40 4.5 39.4 1.0 CB B:GLN119 4.6 35.2 1.0 O B:THR44 4.6 23.9 1.0 CB B:ASN43 4.6 25.1 1.0 NE2 B:HIS13 4.7 26.2 1.0 C B:ILE42 4.7 27.7 1.0 C B:THR44 4.9 23.4 1.0

N.Thiyagarajan, K.R.Acharya. Crystal Structure of Human Angiogenin with An Engineered Loop Exhibits Conformational Flexibility at the Functional Regions of the Molecule Febs Open Bio. V. 3 65 2012.
ISSN: ISSN 2211-5463
PubMed: 23772376
DOI: 10.1016/J.FOB.2012.12.003