Chlorine in PDB 4b41: Crystal Structure of An Amyloid-Beta Binding Single Chain Antibody G7

The structure of Crystal Structure of An Amyloid-Beta Binding Single Chain Antibody G7, PDB code: 4b41 was solved by D.X.Beringer, B.Dorresteijn, L.Rutten, H.Wienk, M.El Khattabi, L.M.J.Kroon-Batenburg, C.T.Verrips, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	49.936 / 1.19
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	29.178, 32.596, 52.197, 103.74, 99.54, 90.62
R / Rfree (%)	13.6 / 16.19

The binding sites of Chlorine atom in the Crystal Structure of An Amyloid-Beta Binding Single Chain Antibody G7 (pdb code 4b41). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of An Amyloid-Beta Binding Single Chain Antibody G7, PDB code: 4b41:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Crystal Structure of An Amyloid-Beta Binding Single Chain Antibody G7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of An Amyloid-Beta Binding Single Chain Antibody G7 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1119 b:28.6 occ:1.00 O A:HOH2161 2.2 21.9 1.0 N A:GLN113 3.1 9.5 1.0 OG1 A:THR112 3.4 9.2 1.0 CA A:THR112 3.7 7.0 1.0 CB A:GLN113 3.8 11.1 1.0 CG A:GLN113 3.9 12.6 1.0 C A:THR112 3.9 8.3 1.0 O A:HOH2160 3.9 8.6 1.0 CA A:GLN113 4.1 8.9 1.0 CB A:THR112 4.1 8.4 1.0 NE2 A:GLN113 4.2 19.1 1.0 CD A:GLN113 4.4 16.1 1.0 O A:HOH2156 4.5 16.1 1.0 O A:GLN113 4.6 8.6 1.0 O A:GLY111 4.6 9.6 1.0 C A:GLN113 4.9 7.6 1.0 N A:THR112 4.9 8.2 1.0

Chlorine binding site 2 out of 4 in the Crystal Structure of An Amyloid-Beta Binding Single Chain Antibody G7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of An Amyloid-Beta Binding Single Chain Antibody G7 within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1120 b:30.4 occ:1.00 CG2 A:VAL12 3.1 15.2 0.1 N A:GLN13 3.1 10.2 1.0 O B:HOH2121 3.2 33.0 1.0 O B:HOH2002 3.2 23.3 1.0 CB A:VAL12 3.6 12.2 0.9 CA A:VAL12 3.7 9.3 0.9 O B:HOH2003 3.7 26.2 1.0 CA A:VAL12 3.8 11.4 0.1 CB A:GLN13 3.8 13.6 1.0 CG A:GLN13 3.9 17.2 1.0 C A:VAL12 3.9 10.6 0.1 C A:VAL12 3.9 8.8 0.9 NE2 B:GLN110 4.0 20.3 1.0 CA A:GLN13 4.0 9.9 1.0 CB A:VAL12 4.0 13.2 0.1 O A:HOH2033 4.1 15.7 1.0 CG1 B:VAL5 4.1 13.7 1.0 CG1 A:VAL12 4.2 13.5 0.9 CD B:GLN110 4.4 16.9 1.0 CG2 B:VAL5 4.4 14.9 1.0 O A:GLN13 4.4 9.6 1.0 CG B:GLN110 4.6 14.0 1.0 CA A:GLY16 4.6 8.2 1.0 CB B:VAL5 4.7 13.2 1.0 O A:HOH2023 4.7 39.7 1.0 C A:GLN13 4.7 8.8 1.0 CA B:VAL5 4.8 11.9 1.0 CG2 A:VAL12 4.9 13.8 0.9 OE1 B:GLN110 5.0 19.0 1.0 CB B:GLN110 5.0 12.9 1.0

Chlorine binding site 3 out of 4 in the Crystal Structure of An Amyloid-Beta Binding Single Chain Antibody G7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of An Amyloid-Beta Binding Single Chain Antibody G7 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1119 b:17.7 occ:1.00 O A:HOH2036 2.9 26.3 1.0 N B:GLN113 3.2 9.5 1.0 NE2 A:GLN81 3.3 9.1 1.0 OG A:SER17 3.3 11.8 1.0 OG1 B:THR112 3.5 9.0 1.0 CA B:THR112 3.8 7.4 1.0 CG B:GLN113 3.9 14.1 1.0 CB B:GLN113 3.9 10.9 1.0 CB A:SER17 3.9 9.6 1.0 C A:LEU18 3.9 7.2 1.0 O A:HOH2034 3.9 9.4 1.0 N A:LEU18 4.0 6.5 1.0 C B:THR112 4.0 7.2 1.0 CA A:LEU18 4.0 6.6 1.0 C A:SER17 4.0 6.9 1.0 N A:ARG19 4.0 7.0 1.0 NE2 B:GLN113 4.1 15.1 1.0 CA B:GLN113 4.1 9.2 1.0 CB B:THR112 4.2 7.6 1.0 CD A:GLN81 4.2 8.5 1.0 O A:LEU18 4.2 8.4 1.0 O A:SER17 4.2 8.2 1.0 OE1 A:GLN81 4.3 10.4 1.0 CD B:GLN113 4.3 15.7 1.0 CB A:ARG19 4.4 8.7 1.0 O B:HOH2120 4.5 15.6 1.0 O B:GLY111 4.6 9.7 1.0 CA A:SER17 4.6 7.6 1.0 O B:GLN113 4.7 8.2 1.0 CA A:ARG19 4.8 7.1 1.0 C B:GLN113 4.9 7.6 1.0 N B:THR112 4.9 7.8 1.0

Chlorine binding site 4 out of 4 in the Crystal Structure of An Amyloid-Beta Binding Single Chain Antibody G7


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of An Amyloid-Beta Binding Single Chain Antibody G7 within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1121 b:30.7 occ:1.00 N B:ARG45 2.9 12.1 1.0 NE2 B:GLN39 3.6 23.7 1.0 CA B:GLN44 3.6 14.8 1.0 CB B:ARG45 3.7 14.3 1.0 C B:GLN44 3.7 13.6 1.0 CB B:GLN44 3.9 17.3 1.0 CA B:ARG45 3.9 12.2 1.0 CG B:GLN44 4.3 23.4 1.0 CD B:GLN39 4.4 19.6 1.0 O B:ARG45 4.5 14.3 1.0 C B:ARG45 4.7 11.1 1.0 O B:LYS43 4.8 20.4 1.0 N B:GLN44 4.9 15.6 1.0 OE1 B:GLN39 4.9 25.1 1.0 O B:GLN44 4.9 13.9 1.0

D.X.Beringer, B.Dorresteijn, L.Rutten, H.Wienk, M.El Khattabi, L.M.J.Kroon-Batenburg, C.T.Verrips. Crystal Structure of An Amyloid-Beta Binding Single Chain Antibody G7 To Be Published.