Chlorine in PDB 4bqm: Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain

All present enzymatic activity of Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain:
3.5.1.2;

The structure of Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain, PDB code: 4bqm was solved by I.M.Ferreira, M.Vollmar, T.Krojer, C.Strain-Damerell, S.Froese, D.Coutandin, E.Williams, N.Burgess-Brown, F.Von Delft, C.H.Arrowsmith, C.Bountra, A.Edwards, S.M.G.Dias, A.L.B.Ambrosio, W.W.Yue, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	65.92 / 2.18
Space group	H 3 2
Cell size a, b, c (Å), α, β, γ (°)	203.613, 203.613, 98.965, 90.00, 90.00, 120.00
R / Rfree (%)	17.7 / 20.3

The binding sites of Chlorine atom in the Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain (pdb code 4bqm). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain, PDB code: 4bqm:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1469 b:94.0 occ:1.00 OD1 A:ASP345 3.2 63.5 1.0 O A:MET341 3.8 43.0 1.0 OH A:TYR322 3.8 38.0 1.0 CG A:MET341 3.8 60.4 1.0 CG A:ASP345 4.1 54.2 1.0 SD A:MET341 4.1 54.9 1.0 CB A:ASP345 4.2 47.7 1.0 NZ A:LYS315 4.2 77.3 1.0 CE1 A:TYR322 4.3 39.8 1.0 N A:ASP345 4.4 36.6 1.0 CA A:ASP345 4.4 38.6 1.0 CZ A:TYR322 4.5 38.2 1.0 C A:MET341 4.7 49.6 1.0 CG A:LYS315 4.7 56.1 1.0 CB A:LEU344 4.7 38.0 1.0 CE2 A:PHE348 4.7 36.9 1.0 CB A:MET341 4.8 48.3 1.0 CA A:MET341 4.9 46.3 1.0 CD2 A:PHE348 4.9 39.4 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1468 b:85.1 occ:1.00 OD1 B:ASP345 3.0 72.9 1.0 OH B:TYR322 3.6 42.7 1.0 CG B:ASP345 4.0 60.4 1.0 CG B:LYS315 4.0 56.2 1.0 CB B:ASP345 4.2 54.8 1.0 CE2 B:PHE348 4.2 43.6 1.0 CA B:ASP345 4.3 46.9 1.0 O B:MET341 4.3 46.6 1.0 CE1 B:TYR322 4.3 46.4 1.0 CZ B:TYR322 4.3 44.7 1.0 CD2 B:PHE348 4.4 46.9 1.0 N B:ASP345 4.4 44.3 1.0 CG B:MET341 4.5 63.0 1.0 SD B:MET341 4.6 69.1 1.0 CD B:LYS315 4.7 61.0 1.0 CB B:LEU344 4.8 46.4 1.0 CB B:LYS315 5.0 55.6 1.0 C B:LEU344 5.0 40.6 1.0

I.M.Ferreira, M.Vollmar, T.Krojer, C.Strain-Damerell, S.Froese, D.Coutandin, E.Williams, N.Burgess-Brown, F.Von Delft, C.H.Arrowsmith, C.Bountra, A.Edwards, S.M.G.Dias, A.L.B.Ambrosio, W.W.Yue. Crystal Structure of Human Liver-Type Glutaminase, Catalytic Domain To Be Published.