Chlorine in PDB 4bso: Crystal Structure of R-Spondin 1 (FU1FU2) - Native

The structure of Crystal Structure of R-Spondin 1 (FU1FU2) - Native, PDB code: 4bso was solved by W.C.Peng, W.De Lau, F.Forneris, J.C.M.Granneman, M.Huch, H.Clevers, P.Gros, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	34.480 / 2.20
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	37.160, 63.900, 92.460, 90.00, 90.00, 90.00
R / Rfree (%)	21.21 / 24.99

The binding sites of Chlorine atom in the Crystal Structure of R-Spondin 1 (FU1FU2) - Native (pdb code 4bso). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of R-Spondin 1 (FU1FU2) - Native, PDB code: 4bso:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of R-Spondin 1 (FU1FU2) - Native


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of R-Spondin 1 (FU1FU2) - Native within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1119 b:66.8 occ:1.00 N A:GLY52 3.2 56.7 1.0 O A:HOH2011 3.9 40.0 1.0 CA A:PRO51 4.0 45.0 1.0 CA A:GLY52 4.0 40.8 1.0 C A:PRO51 4.1 55.0 1.0 C2 A:EDO1116 4.1 56.3 1.0 O2 A:EDO1116 4.6 54.2 1.0 O A:TYR53 4.7 33.3 1.0 CB A:PRO51 4.8 47.0 1.0 N A:TYR53 4.8 51.8 1.0 C A:GLY52 4.9 42.8 1.0 O A:PRO50 5.0 43.2 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of R-Spondin 1 (FU1FU2) - Native


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of R-Spondin 1 (FU1FU2) - Native within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1120 b:60.1 occ:1.00 N A:CYS84 3.1 32.9 1.0 O A:CYS84 3.5 32.7 1.0 CB A:CYS84 3.7 45.3 1.0 CA A:CYS84 3.8 37.1 1.0 CD A:LYS83 4.0 49.0 1.0 CA A:LYS83 4.0 40.6 1.0 NZ A:LYS83 4.0 64.3 1.0 C A:LYS83 4.0 42.5 1.0 CE A:LYS83 4.1 60.8 1.0 C A:CYS84 4.1 39.4 1.0 O A:HOH2018 4.1 49.1 1.0 CB A:LEU90 4.2 33.4 1.0 SG A:CYS84 4.5 44.7 1.0 CG A:LYS83 4.5 43.9 1.0 CD2 A:LEU90 4.5 25.8 1.0 O A:LEU88 4.7 52.2 1.0 CB A:LYS83 4.8 36.2 1.0 N A:LEU90 4.9 30.3 1.0

W.C.Peng, W.De Lau, F.Forneris, J.C.M.Granneman, M.Huch, H.Clevers, P.Gros. Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of Its Receptor LGR5. Cell Rep. V. 3 1885 2013.
ISSN: ISSN 2211-1247
PubMed: 23809763
DOI: 10.1016/J.CELREP.2013.06.009