Atomistry » Chlorine » PDB 4bri-4bzr » 4bve
Atomistry »
  Chlorine »
    PDB 4bri-4bzr »
      4bve »

Chlorine in PDB 4bve: Crystal Structure of Human SIRT3 in Complex with Thioalkylimidate Formed From Thio-Acetyl-Lysine ACS2- Peptide

Enzymatic activity of Crystal Structure of Human SIRT3 in Complex with Thioalkylimidate Formed From Thio-Acetyl-Lysine ACS2- Peptide

All present enzymatic activity of Crystal Structure of Human SIRT3 in Complex with Thioalkylimidate Formed From Thio-Acetyl-Lysine ACS2- Peptide:
6.2.1.1;

Protein crystallography data

The structure of Crystal Structure of Human SIRT3 in Complex with Thioalkylimidate Formed From Thio-Acetyl-Lysine ACS2- Peptide, PDB code: 4bve was solved by M.Gertz, M.Weyand, C.Steegborn, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 34.14 / 2.05
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 80.990, 126.970, 76.490, 90.00, 90.00, 90.00
R / Rfree (%) 16.193 / 20.789

Other elements in 4bve:

The structure of Crystal Structure of Human SIRT3 in Complex with Thioalkylimidate Formed From Thio-Acetyl-Lysine ACS2- Peptide also contains other interesting chemical elements:

Zinc (Zn) 1 atom

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Human SIRT3 in Complex with Thioalkylimidate Formed From Thio-Acetyl-Lysine ACS2- Peptide (pdb code 4bve). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human SIRT3 in Complex with Thioalkylimidate Formed From Thio-Acetyl-Lysine ACS2- Peptide, PDB code: 4bve:

Chlorine binding site 1 out of 1 in 4bve

Go back to Chlorine Binding Sites List in 4bve
Chlorine binding site 1 out of 1 in the Crystal Structure of Human SIRT3 in Complex with Thioalkylimidate Formed From Thio-Acetyl-Lysine ACS2- Peptide


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human SIRT3 in Complex with Thioalkylimidate Formed From Thio-Acetyl-Lysine ACS2- Peptide within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1396

b:48.3
occ:1.00
N A:GLN300 3.5 20.5 1.0
O A:HOH2166 3.8 40.9 1.0
O A:HOH2165 4.0 26.5 1.0
CA A:PRO299 4.0 18.4 1.0
CG A:GLN300 4.0 34.9 1.0
CB A:GLN300 4.1 28.1 1.0
CB A:PRO299 4.2 19.4 1.0
C A:PRO299 4.3 17.6 1.0
CA A:GLN300 4.4 24.6 1.0

Reference:

M.Gertz, F.Fischer, G.T.T.Nguyen, M.Lakshminarasimhan, M.Schutkowski, M.Weyand, C.Steegborn. Ex-527 Inhibits Sirtuins By Exploiting Their Unique Nad+-Dependent Deacetylation Mechanism Proc.Natl.Acad.Sci.Usa V. 110 E2772 2013.
ISSN: ISSN 0027-8424
PubMed: 23840057
DOI: 10.1073/PNAS.1303628110
Page generated: Sat Dec 12 10:27:41 2020

Last articles

Zn in 7VD8
Zn in 7V1R
Zn in 7V1Q
Zn in 7VPF
Zn in 7T85
Zn in 7T5F
Zn in 7NF9
Zn in 7M4M
Zn in 7M4O
Zn in 7M4N
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy