Chlorine in PDB 4c99: Mouse ZNRF3 Ectodomain in Complex with Mouse RSPO2 FU1-FU2 Crystal Form I

The structure of Mouse ZNRF3 Ectodomain in Complex with Mouse RSPO2 FU1-FU2 Crystal Form I, PDB code: 4c99 was solved by M.Zebisch, E.Y.Jones, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	66.46 / 2.80
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	59.800, 77.206, 130.611, 90.00, 90.00, 90.00
R / Rfree (%)	23.616 / 32.285

The binding sites of Chlorine atom in the Mouse ZNRF3 Ectodomain in Complex with Mouse RSPO2 FU1-FU2 Crystal Form I (pdb code 4c99). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Mouse ZNRF3 Ectodomain in Complex with Mouse RSPO2 FU1-FU2 Crystal Form I, PDB code: 4c99:

Chlorine binding site 1 out of 1 in the Mouse ZNRF3 Ectodomain in Complex with Mouse RSPO2 FU1-FU2 Crystal Form I


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Mouse ZNRF3 Ectodomain in Complex with Mouse RSPO2 FU1-FU2 Crystal Form I within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1206 b:79.1 occ:1.00 NH2 C:ARG199 3.0 47.0 1.0 NH2 A:ARG199 3.2 49.6 1.0 NH1 C:ARG199 3.3 42.2 1.0 NH1 A:ARG199 3.5 40.1 1.0 CZ C:ARG199 3.6 41.1 1.0 N A:GLU94 3.7 36.4 1.0 CZ A:ARG199 3.7 42.1 1.0 CA A:GLY93 3.9 42.2 1.0 C A:GLY93 4.3 38.1 1.0 CB A:GLU94 4.5 54.2 1.0 O A:GLY116 4.6 59.6 1.0 CA A:GLU94 4.7 44.7 1.0 NE C:ARG199 4.9 41.4 1.0 C A:GLY116 4.9 50.1 1.0 NE A:ARG199 4.9 38.9 1.0 O A:GLU92 4.9 47.3 1.0

M.Zebisch, Y.Xu, C.Krastev, B.T.Macdonald, M.Chen, R.J.C.Gilbert, X.He, E.Y.Jones. Structural and Molecular Basis of ZNRF3/RNF43 Transmembrane Ubiquitin Ligase Inhibition By the Wnt Agonist R-Spondin. Nat.Commun. V. 4 2787 2013.
ISSN: ISSN 2041-1723
PubMed: 24225776
DOI: 10.1038/NCOMMS3787