Chlorine in PDB 4c9z: Crystal Structure of SIAH1 at 1.95 A Resolution

The structure of Crystal Structure of SIAH1 at 1.95 A Resolution, PDB code: 4c9z was solved by V.Rimsa, T.C.Eadsforth, W.N.Hunter, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	40.00 / 1.95
Space group	I 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	75.140, 104.590, 133.160, 90.00, 90.00, 90.00
R / Rfree (%)	19.761 / 23.855

The structure of Crystal Structure of SIAH1 at 1.95 A Resolution also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

The binding sites of Chlorine atom in the Crystal Structure of SIAH1 at 1.95 A Resolution (pdb code 4c9z). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 4 binding sites of Chlorine where determined in the Crystal Structure of SIAH1 at 1.95 A Resolution, PDB code: 4c9z:
Jump to Chlorine binding site number: 1; 2; 3; 4;

Chlorine binding site 1 out of 4 in the Crystal Structure of SIAH1 at 1.95 A Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of SIAH1 at 1.95 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1283 b:66.7 occ:1.00 NH1 A:ARG224 3.7 23.9 1.0 O A:HOH2044 3.8 26.3 1.0 NH2 A:ARG224 3.8 22.5 1.0 CZ A:ARG224 4.2 25.4 1.0 O A:HOH2045 4.4 32.7 1.0 O A:HOH2046 4.6 35.5 1.0

Chlorine binding site 2 out of 4 in the Crystal Structure of SIAH1 at 1.95 A Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of SIAH1 at 1.95 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1284 b:81.5 occ:1.00 NH2 A:ARG233 3.8 54.5 1.0 NH1 A:ARG233 3.9 50.3 1.0 CZ A:ARG233 4.3 52.8 1.0 O1 A:GOL1286 4.9 64.0 1.0

Chlorine binding site 3 out of 4 in the Crystal Structure of SIAH1 at 1.95 A Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of SIAH1 at 1.95 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1285 b:82.4 occ:1.00 NH1 A:ARG232 3.4 57.0 1.0 ND1 A:HIS230 3.4 51.3 0.5 NH2 A:ARG232 3.6 48.2 1.0 CE1 A:HIS230 4.0 47.1 0.5 CZ A:ARG232 4.0 53.4 1.0 CG A:HIS230 4.7 48.9 0.5 O B:HOH2062 4.7 33.4 1.0 CD2 A:HIS230 4.9 59.0 0.5

Chlorine binding site 4 out of 4 in the Crystal Structure of SIAH1 at 1.95 A Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of SIAH1 at 1.95 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1286 b:70.3 occ:1.00 NH1 B:ARG224 3.4 32.3 1.0 NH2 B:ARG224 4.1 32.5 1.0 CZ B:ARG224 4.2 39.7 1.0 O A:HOH2103 4.5 48.7 1.0 O B:HOH2029 4.6 41.5 1.0

V.Rimsa, T.C.Eadsforth, W.N.Hunter. Two High-Resolution Structures of the Human E3 Ubiquitin Ligase SIAH1. Acta Crystallogr.,Sect.F V. 96 1339 2013.
ISSN: ISSN 1744-3091
PubMed: 24316825
DOI: 10.1107/S1744309113031448