Atomistry » Chlorine » PDB 4ced-4ck4 » 4cf6
Atomistry »
  Chlorine »
    PDB 4ced-4ck4 »
      4cf6 »

Chlorine in PDB 4cf6: Crystal Structure of the Complex of the P187S Variant of Human Nad(P)H:Quinone Oxidoreductase with Cibacron Blue at 2.7 A Resolution

Enzymatic activity of Crystal Structure of the Complex of the P187S Variant of Human Nad(P)H:Quinone Oxidoreductase with Cibacron Blue at 2.7 A Resolution

All present enzymatic activity of Crystal Structure of the Complex of the P187S Variant of Human Nad(P)H:Quinone Oxidoreductase with Cibacron Blue at 2.7 A Resolution:
1.6.5.2;

Protein crystallography data

The structure of Crystal Structure of the Complex of the P187S Variant of Human Nad(P)H:Quinone Oxidoreductase with Cibacron Blue at 2.7 A Resolution, PDB code: 4cf6 was solved by W.D.Lienhart, V.Gudipati, M.K.Uhl, A.Binter, S.Pulido, R.Saf, K.Zangger, K.Gruber, P.Macheroux, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 46.217 / 2.69
Space group I 2 2 2
Cell size a, b, c (Å), α, β, γ (°) 104.167, 104.563, 118.566, 90.00, 90.00, 90.00
R / Rfree (%) 18.47 / 20.74

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of the Complex of the P187S Variant of Human Nad(P)H:Quinone Oxidoreductase with Cibacron Blue at 2.7 A Resolution (pdb code 4cf6). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of the Complex of the P187S Variant of Human Nad(P)H:Quinone Oxidoreductase with Cibacron Blue at 2.7 A Resolution, PDB code: 4cf6:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in 4cf6

Go back to Chlorine Binding Sites List in 4cf6
Chlorine binding site 1 out of 2 in the Crystal Structure of the Complex of the P187S Variant of Human Nad(P)H:Quinone Oxidoreductase with Cibacron Blue at 2.7 A Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Complex of the P187S Variant of Human Nad(P)H:Quinone Oxidoreductase with Cibacron Blue at 2.7 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl1275

b:64.9
occ:0.86
 CL A:CBD1275 0.0 64.9 0.9
CC2 A:CBD1275 1.7 64.0 0.9
NC1 A:CBD1275 2.7 62.4 0.9
NC3 A:CBD1275 2.7 62.2 0.9
CD2 B:TYR129 3.6 53.0 1.0
CE2 B:TYR129 3.9 50.2 1.0
CC4 A:CBD1275 3.9 61.6 0.9
CC6 A:CBD1275 3.9 60.4 0.9
NC5 A:CBD1275 4.4 60.4 0.9
CG B:TYR129 4.7 50.5 1.0
CZ B:PHE233 4.7 58.6 1.0
CB3 A:CBD1275 4.7 51.9 0.9

Chlorine binding site 2 out of 2 in 4cf6

Go back to Chlorine Binding Sites List in 4cf6
Chlorine binding site 2 out of 2 in the Crystal Structure of the Complex of the P187S Variant of Human Nad(P)H:Quinone Oxidoreductase with Cibacron Blue at 2.7 A Resolution


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Complex of the P187S Variant of Human Nad(P)H:Quinone Oxidoreductase with Cibacron Blue at 2.7 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl1276

b:63.5
occ:0.75
 CL B:CBD1276 0.0 63.5 0.8
CC2 B:CBD1276 1.7 61.0 0.8
NC3 B:CBD1276 2.7 61.0 0.8
NC1 B:CBD1276 2.7 61.5 0.8
CB A:PHE233 3.5 62.6 1.0
O A:PHE233 3.6 63.2 1.0
O2B B:CBD1276 3.8 61.9 0.8
CC4 B:CBD1276 3.9 58.9 0.8
CC6 B:CBD1276 3.9 60.3 0.8
C A:PHE233 4.1 63.2 1.0
NC5 B:CBD1276 4.4 58.0 0.8
CA A:PHE233 4.4 62.2 1.0
CG A:PHE233 4.5 62.7 1.0
CD2 A:PHE233 4.8 62.7 1.0
N A:GLN234 4.9 61.7 1.0

Reference:

W.D.Lienhart, V.Gudipati, M.K.Uhl, A.Binter, S.Pulido, R.Saf, K.Zangger, K.Gruber, P.Macheroux. Collapse of the Native Structure By A Single Amino Acid Exchange in Human Nad(P)H:Quinone Oxidoreductase (NQO1). Febs J. V. 281 4691 2014.
ISSN: ISSN 1742-464X
PubMed: 25143260
DOI: 10.1111/FEBS.12975
Page generated: Sun Jul 21 11:10:47 2024

Last articles

Zn in 9J0N
Zn in 9J0O
Zn in 9J0P
Zn in 9FJX
Zn in 9EKB
Zn in 9C0F
Zn in 9CAH
Zn in 9CH0
Zn in 9CH3
Zn in 9CH1
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy