Chlorine in PDB 4co6: Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex

The structure of Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex, PDB code: 4co6 was solved by F.Yabukarksi, P.Lawrence, N.Tarbouriech, J.M.Bourhis, M.R.Jensen, R.W.H.Ruigrok, M.Blackledge, V.Volchkov, M.Jamin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.189 / 2.50
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	82.890, 98.960, 156.910, 90.00, 90.00, 90.00
R / Rfree (%)	19.16 / 25.93

The structure of Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex also contains other interesting chemical elements:

Bromine

(Br)

2 atoms

The binding sites of Chlorine atom in the Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex (pdb code 4co6). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 7 binding sites of Chlorine where determined in the Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex, PDB code: 4co6:
Jump to Chlorine binding site number: 1; 2; 3; 4; 5; 6; 7;

Chlorine binding site 1 out of 7 in the Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1372 b:48.5 occ:1.00 NE2 A:GLN212 2.7 83.4 1.0 CG A:GLN212 3.6 69.7 1.0 CD A:GLN212 3.6 78.6 1.0 NE A:ARG60 3.7 70.9 1.0 N A:TRP213 3.8 61.3 1.0 CB A:ARG60 3.8 60.9 1.0 CA A:TRP213 3.8 53.6 1.0 CB A:TRP213 4.0 48.0 1.0 C A:GLN212 4.1 68.1 1.0 CB A:GLN212 4.1 66.6 1.0 CD1 A:TRP213 4.2 39.7 1.0 CD A:ARG60 4.3 69.4 1.0 OG1 A:THR210 4.3 68.0 1.0 CG A:ARG60 4.4 67.2 1.0 O A:GLN212 4.4 72.9 1.0 O A:THR143 4.5 62.5 1.0 CG A:TRP213 4.5 42.7 1.0 CA A:PRO144 4.7 55.0 1.0 CZ A:ARG60 4.8 67.3 1.0 CA A:GLN212 4.8 67.3 1.0 OE1 A:GLN212 4.8 82.7 1.0 NH2 A:ARG60 4.8 68.0 1.0

Chlorine binding site 2 out of 7 in the Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1373 b:41.0 occ:1.00 O A:HOH2011 2.6 53.4 1.0 C A:LYS245 3.5 49.6 1.0 CA A:LYS245 3.5 52.9 1.0 CB A:LYS245 3.6 50.4 1.0 N A:ALA248 3.6 55.1 1.0 O A:LYS245 3.7 39.9 1.0 N A:ARG247 3.7 54.0 1.0 CD1 A:ILE166 3.8 50.5 1.0 N A:GLY246 4.0 59.1 1.0 CB A:ARG247 4.0 49.6 1.0 CG1 A:VAL162 4.0 46.7 1.0 CB A:ALA248 4.1 60.3 1.0 CA A:ARG247 4.2 57.4 1.0 CD A:LYS245 4.3 51.7 1.0 C A:ARG247 4.4 55.4 1.0 CA A:ALA248 4.5 57.9 1.0 CG A:LYS245 4.5 50.0 1.0 CG A:ARG247 4.5 46.6 1.0 CG1 A:ILE166 4.6 39.2 1.0 C A:GLY246 4.6 59.9 1.0 CA A:GLY246 4.9 63.2 1.0 N A:LYS245 4.9 53.9 1.0

Chlorine binding site 3 out of 7 in the Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 3 of Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1374 b:43.4 occ:1.00 OG A:SER366 2.9 40.3 1.0 CD A:PRO280 3.4 49.8 1.0 CG A:PRO280 3.4 52.5 1.0 CE1 D:TYR28 3.6 41.8 1.0 CB A:SER366 3.7 31.9 1.0 N A:ALA281 3.7 38.1 1.0 CB A:TYR279 3.8 37.7 1.0 NE2 A:HIS370 3.8 64.4 1.0 CD1 D:TYR28 3.9 47.2 1.0 N A:PRO280 3.9 44.3 1.0 CB A:ALA281 4.0 30.6 1.0 CA A:SER366 4.1 32.2 1.0 CD2 A:HIS370 4.2 68.8 1.0 C A:TYR279 4.3 37.2 1.0 CA A:TYR279 4.4 38.0 1.0 CG A:TYR279 4.4 41.6 1.0 CA A:ALA281 4.4 33.2 1.0 CB A:PRO280 4.5 44.7 1.0 C A:PRO280 4.5 44.9 1.0 CA A:PRO280 4.6 46.6 1.0 CZ D:TYR28 4.7 49.2 1.0 CD1 A:TYR279 4.8 48.4 1.0 O A:SER366 4.8 49.7 1.0 C A:SER366 5.0 48.9 1.0

Chlorine binding site 4 out of 7 in the Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 4 of Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1375 b:49.0 occ:1.00 N A:GLU82 3.4 44.6 1.0 CB A:SER243 3.7 43.4 1.0 CB A:SER81 3.7 45.3 1.0 CA A:SER81 3.8 44.5 1.0 CG A:LYS245 3.8 50.0 1.0 CE A:LYS245 4.0 54.4 1.0 C A:SER81 4.1 41.4 1.0 OG A:SER243 4.2 51.5 1.0 CB A:GLU82 4.2 61.5 1.0 CA A:GLU82 4.4 50.1 1.0 CG A:GLU82 4.4 69.3 1.0 CD A:LYS245 4.5 51.7 1.0 CA A:SER243 4.7 58.2 1.0 CE1 A:TYR80 4.8 38.3 1.0 CB A:LYS245 4.9 50.4 1.0

Chlorine binding site 5 out of 7 in the Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 5 of Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl1377 b:41.0 occ:1.00 O A:ASN285 3.8 39.3 1.0 O A:HOH2028 3.8 34.3 1.0 CA A:GLU286 4.0 29.6 1.0 C A:ASN285 4.1 36.5 1.0 N A:GLU286 4.3 32.3 1.0 CG A:GLU286 4.5 33.5 1.0 CB A:ASN285 4.5 37.7 1.0 CB A:GLU286 4.8 27.8 1.0 C A:GLU286 5.0 28.9 1.0 CA A:ASN285 5.0 33.5 1.0

Chlorine binding site 6 out of 7 in the Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 6 of Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1370 b:40.1 occ:1.00 O B:HOH2011 3.1 42.9 1.0 CG B:GLN212 3.6 49.3 1.0 CA B:TRP213 3.8 43.6 1.0 N B:TRP213 3.8 50.1 1.0 CB B:ARG60 3.9 66.2 1.0 CB B:TRP213 3.9 42.8 1.0 NE B:ARG60 4.0 62.7 1.0 OE1 B:GLN212 4.1 61.8 1.0 C B:GLN212 4.1 53.3 1.0 CD1 B:TRP213 4.2 50.3 1.0 CG B:ARG60 4.3 66.8 1.0 CB B:GLN212 4.3 54.9 1.0 O B:GLN212 4.3 54.9 1.0 CD B:GLN212 4.3 56.7 1.0 O B:THR143 4.4 54.4 1.0 CG B:TRP213 4.5 44.2 1.0 OG1 B:THR210 4.5 53.8 1.0 NH2 B:ARG60 4.6 48.5 1.0 CD B:ARG60 4.7 65.7 1.0 CZ B:ARG60 4.7 54.3 1.0 CA B:PRO144 4.8 46.1 1.0 CA B:GLN212 4.9 57.3 1.0

Chlorine binding site 7 out of 7 in the Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 7 of Crystal Structure of the Nipah Virus Rna Free Nucleoprotein-Phosphoprotein Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1371 b:56.4 occ:1.00 CA B:MSE264 3.4 46.1 1.0 N B:GLY266 3.4 32.5 1.0 N B:PHE267 3.5 36.0 1.0 C B:MSE264 3.5 47.9 1.0 N B:ALA265 3.8 41.4 1.0 CA B:GLY266 3.9 35.2 1.0 O B:PHE322 3.9 37.5 1.0 CD B:PRO324 3.9 37.5 1.0 O B:MSE264 4.0 47.7 1.0 CB B:PHE267 4.1 36.7 1.0 C B:GLY266 4.1 34.6 1.0 N B:MSE264 4.2 57.6 1.0 CB B:MSE264 4.3 42.7 1.0 C B:ALA265 4.3 55.5 1.0 CA B:PHE267 4.4 39.0 1.0 CA B:ALA323 4.4 44.5 1.0 CG B:PRO324 4.4 31.8 1.0 C B:PHE322 4.5 36.2 1.0 CG B:MSE264 4.6 47.1 1.0 CA B:ALA265 4.6 36.0 1.0 N B:ALA323 4.8 42.2 1.0 OH B:TYR327 4.9 42.0 1.0 N B:PRO324 4.9 44.5 1.0

F.Yabukarksi, P.Lawrence, N.Tarbouriech, J.M.Bourhis, E.Delaforge, M.R.Jensen, R.W.H.Ruigrok, M.Blackledge, V.Volchkov, M.Jamin. Structure of Nipah Virus Unassembled Nucleoprotein in Complex with Its Viral Chaperone. Nat.Struct.Mol.Biol. V. 21 754 2014.
ISSN: ISSN 1545-9993
PubMed: 25108352
DOI: 10.1038/NSMB.2868