Chlorine in PDB 4cxl: Human Insulin Analogue (D-PROB8)-Insulin

The structure of Human Insulin Analogue (D-PROB8)-Insulin, PDB code: 4cxl was solved by L.Kosinova, V.Veverka, P.Novotna, M.Collinsova, M.Urbanova, J.Jiracek, N.R.Moody, J.P.Turkenburg, A.M.Brzozowski, L.Zakova, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.33 / 1.50
Space group	I 21 3
Cell size a, b, c (Å), α, β, γ (°)	78.660, 78.660, 78.660, 90.00, 90.00, 90.00
R / Rfree (%)	16.694 / 19.713

The binding sites of Chlorine atom in the Human Insulin Analogue (D-PROB8)-Insulin (pdb code 4cxl). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human Insulin Analogue (D-PROB8)-Insulin, PDB code: 4cxl:

Chlorine binding site 1 out of 1 in the Human Insulin Analogue (D-PROB8)-Insulin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Human Insulin Analogue (D-PROB8)-Insulin within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl1001 b:78.6 occ:0.33 O B:HOH2017 4.5 45.0 1.0 O B:LEU17 4.7 20.2 1.0 CZ B:PHE1 4.9 37.6 1.0

L.Kosinova, V.Veverka, P.Novotna, M.Collinsova, M.Urbanova, N.R.Moody, J.P.Turkenburg, J.Jiracek, A.M.Brzozowski, L.Zakova. An Insight Into Structural and Biological Relevance of the T/R Transition of the B-Chain N-Terminus in Human Insulin. Biochemistry V. 53 3392 2014.
ISSN: ISSN 0006-2960
PubMed: 24819248
DOI: 10.1021/BI500073Z