Chlorine in PDB 4czv: Structure of the Neurospora Crassa PAN2 WD40 Domain

All present enzymatic activity of Structure of the Neurospora Crassa PAN2 WD40 Domain:
3.1.13.4;

The structure of Structure of the Neurospora Crassa PAN2 WD40 Domain, PDB code: 4czv was solved by D.Peter, S.Jonas, E.Izaurralde, O.Weichenrieder, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.32 / 2.10
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	60.990, 71.510, 77.120, 90.00, 94.65, 90.00
R / Rfree (%)	18.17 / 21.62

The binding sites of Chlorine atom in the Structure of the Neurospora Crassa PAN2 WD40 Domain (pdb code 4czv). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Structure of the Neurospora Crassa PAN2 WD40 Domain, PDB code: 4czv:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Structure of the Neurospora Crassa PAN2 WD40 Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of the Neurospora Crassa PAN2 WD40 Domain within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl401 b:22.9 occ:1.00 OG A:SER16 3.0 22.3 1.0 NH1 A:ARG58 3.2 26.5 1.0 N A:SER16 3.3 21.2 1.0 CB A:SER16 3.5 21.3 1.0 NH2 A:ARG58 3.7 25.3 1.0 CD1 A:TYR14 3.7 21.0 1.0 CD2 A:HIS19 3.8 24.7 1.0 CB A:HIS19 3.8 27.2 1.0 CZ A:ARG58 3.9 25.6 1.0 CA A:SER16 4.0 21.1 1.0 O A:ALA13 4.0 22.5 1.0 CG A:HIS19 4.1 25.8 1.0 CE1 A:TYR14 4.1 21.1 1.0 C A:PRO15 4.3 20.9 1.0 CA A:PRO15 4.3 21.3 1.0 CG2 A:ILE18 4.6 33.2 1.0 O A:SER16 4.6 21.7 1.0 C A:SER16 4.7 21.9 1.0 CA A:HIS19 4.7 27.7 1.0 N A:HIS19 4.7 26.3 1.0 CG A:TYR14 4.8 21.0 1.0 CA A:TYR14 4.8 20.8 1.0

Chlorine binding site 2 out of 2 in the Structure of the Neurospora Crassa PAN2 WD40 Domain


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Structure of the Neurospora Crassa PAN2 WD40 Domain within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl400 b:20.0 occ:1.00 OG B:SER16 3.1 26.5 1.0 N B:SER16 3.1 25.5 1.0 CB B:SER16 3.3 25.2 1.0 NH1 B:ARG58 3.4 22.2 1.0 NH2 B:ARG58 3.6 22.3 1.0 O B:ALA13 3.7 23.2 1.0 CD1 B:TYR14 3.8 23.2 1.0 CA B:SER16 3.8 24.7 1.0 CB B:HIS19 3.8 24.7 1.0 CZ B:ARG58 3.9 22.1 1.0 CD2 B:HIS19 3.9 21.9 1.0 C B:PRO15 4.1 23.7 1.0 CA B:PRO15 4.2 23.8 1.0 CG B:HIS19 4.2 22.2 1.0 CE1 B:TYR14 4.3 22.4 1.0 O B:SER16 4.5 24.4 1.0 C B:SER16 4.6 24.7 1.0 CA B:TYR14 4.6 23.7 1.0 C B:ALA13 4.8 23.4 1.0 CG2 B:ILE18 4.8 27.0 1.0 CG B:TYR14 4.8 23.4 1.0 CA B:HIS19 4.8 25.0 1.0 N B:HIS19 4.9 24.7 1.0 O B:HOH2020 4.9 33.0 1.0 CB B:PRO15 5.0 24.6 1.0

S.Jonas, M.Christie, D.Peter, D.Bhandari, B.Loh, E.Huntzinger, O.Weichenrieder, E.Izaurralde. An Asymmetric PAN3 Dimer Recruits A Single PAN2 Exonuclease to Mediate Mrna Deadenylation and Decay. Nat.Struct.Mol.Biol. V. 21 599 2014.
ISSN: ISSN 1545-9993
PubMed: 24880343
DOI: 10.1038/NSMB.2837