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Atomistry » Chlorine » PDB 4d0m-4d9z » 4d1s | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4d0m-4d9z » 4d1s » |
Chlorine in PDB 4d1s: Pyrrole-3-Carboxamides As Potent and Selective JAK2 InhibitorsEnzymatic activity of Pyrrole-3-Carboxamides As Potent and Selective JAK2 Inhibitors
All present enzymatic activity of Pyrrole-3-Carboxamides As Potent and Selective JAK2 Inhibitors:
2.7.10.2; Protein crystallography data
The structure of Pyrrole-3-Carboxamides As Potent and Selective JAK2 Inhibitors, PDB code: 4d1s
was solved by
J.Bertrand,
G.Canevari,
M.Fasolini,
M.G.Brasca,
M.Nesi,
N.Avanzi,
D.Ballinari,
T.Bandiera,
S.Bindi,
D.Carenzi,
D.Casero,
L.Ceriani,
M.Ciomei,
A.Cirla,
M.Colombo,
S.Cribioli,
C.Cristiani,
F.Della Vedova,
G.Fachin,
E.R.Felder,
A.Galvani,
A.Isacchi,
D.Mirizzi,
I.Motto,
A.Panzeri,
E.Pesenti,
P.Vianello,
P.Gnocchi,
D.Donati,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Pyrrole-3-Carboxamides As Potent and Selective JAK2 Inhibitors
(pdb code 4d1s). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Pyrrole-3-Carboxamides As Potent and Selective JAK2 Inhibitors, PDB code: 4d1s: Chlorine binding site 1 out of 1 in 4d1sGo back to Chlorine Binding Sites List in 4d1s
Chlorine binding site 1 out
of 1 in the Pyrrole-3-Carboxamides As Potent and Selective JAK2 Inhibitors
Mono view Stereo pair view
Reference:
M.G.Brasca,
M.Nesi,
N.Avanzi,
D.Ballinari,
T.Bandiera,
J.Bertrand,
S.Bindi,
G.Canevari,
D.Carenzi,
D.Casero,
L.Ceriani,
M.Ciomei,
A.Cirla,
M.Colombo,
S.Cribioli,
C.Cristiani,
F.Della Vedova,
G.Fachin,
M.Fasolini,
E.R.Felder,
A.Galvani,
A.Isacchi,
D.Mirizzi,
I.Motto,
A.Panzeri,
E.Pesenti,
P.Vianello,
P.Gnocchi,
D.Donati.
Pyrrole-3-Carboxamides As Potent and Selective JAK2 Inhibitors. Bioorg.Med.Chem. V. 22 4998 2014.
Page generated: Sat Dec 12 10:31:03 2020
ISSN: ISSN 0968-0896 PubMed: 25009002 DOI: 10.1016/J.BMC.2014.06.025 |
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