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Atomistry » Chlorine » PDB 4d0m-4d9z » 4d3v » |
Chlorine in PDB 4d3v: Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with N-{3-[(1S)-2-(3-{(Z)-[Amino(Thiophen-2-Yl) Methylidene]Amino}Phenoxy)-1-Hydroxyethyl]Phenyl}Thiophene-2- CarboximidamideEnzymatic activity of Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with N-{3-[(1S)-2-(3-{(Z)-[Amino(Thiophen-2-Yl) Methylidene]Amino}Phenoxy)-1-Hydroxyethyl]Phenyl}Thiophene-2- Carboximidamide
All present enzymatic activity of Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with N-{3-[(1S)-2-(3-{(Z)-[Amino(Thiophen-2-Yl) Methylidene]Amino}Phenoxy)-1-Hydroxyethyl]Phenyl}Thiophene-2- Carboximidamide:
1.14.13.165; Protein crystallography data
The structure of Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with N-{3-[(1S)-2-(3-{(Z)-[Amino(Thiophen-2-Yl) Methylidene]Amino}Phenoxy)-1-Hydroxyethyl]Phenyl}Thiophene-2- Carboximidamide, PDB code: 4d3v
was solved by
J.K.Holden,
T.L.Poulos,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4d3v:
The structure of Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with N-{3-[(1S)-2-(3-{(Z)-[Amino(Thiophen-2-Yl) Methylidene]Amino}Phenoxy)-1-Hydroxyethyl]Phenyl}Thiophene-2- Carboximidamide also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with N-{3-[(1S)-2-(3-{(Z)-[Amino(Thiophen-2-Yl) Methylidene]Amino}Phenoxy)-1-Hydroxyethyl]Phenyl}Thiophene-2- Carboximidamide
(pdb code 4d3v). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with N-{3-[(1S)-2-(3-{(Z)-[Amino(Thiophen-2-Yl) Methylidene]Amino}Phenoxy)-1-Hydroxyethyl]Phenyl}Thiophene-2- Carboximidamide, PDB code: 4d3v: Chlorine binding site 1 out of 1 in 4d3vGo back to Chlorine Binding Sites List in 4d3v
Chlorine binding site 1 out
of 1 in the Structure of Bacillus Subtilis Nitric Oxide Synthase I218V in Complex with N-{3-[(1S)-2-(3-{(Z)-[Amino(Thiophen-2-Yl) Methylidene]Amino}Phenoxy)-1-Hydroxyethyl]Phenyl}Thiophene-2- Carboximidamide
Mono view Stereo pair view
Reference:
J.K.Holden,
S.Kang,
S.A.Hollingsworth,
H.Li,
N.Lim,
S.Chen,
H.Huang,
F.Xue,
W.Tang,
R.B.Silverman,
T.L.Poulos.
Structure-Based Design of Bacterial Nitric Oxide Synthase Inhibitors. J.Med.Chem. V. 58 994 2015.
Page generated: Sat Dec 12 10:31:10 2020
ISSN: ISSN 0022-2623 PubMed: 25522110 DOI: 10.1021/JM501723P |
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