Chlorine in PDB 4d94: Crystal Structure of TEP1R

The structure of Crystal Structure of TEP1R, PDB code: 4d94 was solved by B.V.Le, M.Williams, S.Logarajah, R.H.G.Baxter, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.87 / 2.70
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	150.515, 150.515, 226.315, 90.00, 90.00, 90.00
R / Rfree (%)	21.9 / 24.4

The structure of Crystal Structure of TEP1R also contains other interesting chemical elements:

Sodium

(Na)

2 atoms

The binding sites of Chlorine atom in the Crystal Structure of TEP1R (pdb code 4d94). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of TEP1R, PDB code: 4d94:

Chlorine binding site 1 out of 1 in the Crystal Structure of TEP1R


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of TEP1R within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl2007 b:43.7 occ:1.00 OG A:SER921 3.1 37.2 1.0 NE2 A:GLN976 3.1 34.2 1.0 N A:VAL922 3.1 38.8 1.0 N A:PHE923 3.3 38.1 1.0 N A:ALA967 3.4 36.5 1.0 CA A:LYS966 3.6 38.5 1.0 O A:ALA967 3.7 39.8 1.0 CB A:VAL922 3.8 36.3 1.0 CB A:PHE923 3.8 42.0 1.0 CB A:LYS966 3.8 38.0 1.0 CA A:VAL922 3.8 37.6 1.0 C A:SER921 3.8 39.3 1.0 CA A:SER921 3.9 38.9 1.0 CB A:SER921 3.9 37.9 1.0 C A:LYS966 4.0 37.5 1.0 CG A:GLN976 4.1 35.0 1.0 CD A:GLN976 4.1 34.7 1.0 C A:VAL922 4.1 37.9 1.0 CA A:PHE923 4.2 40.8 1.0 CD2 A:LEU985 4.4 33.4 1.0 CA A:ALA967 4.4 35.8 1.0 C A:ALA967 4.5 37.8 1.0 O A:HOH2268 4.6 46.4 1.0 CG2 A:VAL922 4.7 35.6 1.0 CD1 A:LEU985 4.7 31.2 1.0 CB A:GLN976 4.7 37.1 1.0 N A:LYS966 4.8 42.0 1.0 CG1 A:VAL922 4.8 36.6 1.0 O A:SER921 4.9 39.8 1.0 CB A:ALA967 4.9 34.6 1.0 O A:ASP965 5.0 46.8 1.0

B.V.Le, M.Williams, S.Logarajah, R.H.Baxter. Molecular Basis For Genetic Resistance of Anopheles Gambiae to Plasmodium: Structural Analysis of TEP1 Susceptible and Resistant Alleles. Plos Pathog. V. 8 02958 2012.
ISSN: ISSN 1553-7366
PubMed: 23055931
DOI: 10.1371/JOURNAL.PPAT.1002958