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Chlorine in PDB 4dfj: Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(Aminopentinyl)- Dttp

Enzymatic activity of Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(Aminopentinyl)- Dttp

All present enzymatic activity of Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(Aminopentinyl)- Dttp:
2.7.7.7;

Protein crystallography data

The structure of Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(Aminopentinyl)- Dttp, PDB code: 4dfj was solved by K.Bergen, A.Steck, S.Struett, A.Baccaro, W.Welte, K.Diederichs, A.Marx, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 41.81 / 1.90
Space group P 31 2 1
Cell size a, b, c (Å), α, β, γ (°) 108.880, 108.880, 90.440, 90.00, 90.00, 120.00
R / Rfree (%) 18 / 20.4

Other elements in 4dfj:

The structure of Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(Aminopentinyl)- Dttp also contains other interesting chemical elements:

Magnesium (Mg) 8 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(Aminopentinyl)- Dttp (pdb code 4dfj). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(Aminopentinyl)- Dttp, PDB code: 4dfj:

Chlorine binding site 1 out of 1 in 4dfj

Go back to Chlorine Binding Sites List in 4dfj
Chlorine binding site 1 out of 1 in the Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(Aminopentinyl)- Dttp


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Large Fragment of Dna Polymerase I From Thermus Aquaticus in A Closed Ternary Complex with 5-(Aminopentinyl)- Dttp within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Cl203

b:52.9
occ:1.00
O B:HOH301 2.5 51.1 1.0
N4 B:DOC112 2.8 25.5 1.0
N34 A:0KL903 3.2 48.7 1.0
C33 A:0KL903 3.5 46.6 1.0
N4 B:DC111 3.6 25.8 1.0
O B:HOH306 3.7 50.0 1.0
C5 B:DC111 3.8 25.0 1.0
C4 B:DOC112 3.8 25.0 1.0
C5 B:DOC112 3.9 23.6 1.0
C4 B:DC111 3.9 25.1 1.0
O A:HOH1006 4.5 39.0 1.0
O4 A:0KL903 4.5 29.4 1.0
OG1 A:THR664 4.7 54.0 1.0
C6 B:DC111 4.7 26.5 1.0
N6 C:DA204 4.8 27.4 1.0
O B:HOH321 4.8 44.8 1.0
O B:HOH322 4.9 41.1 1.0
N3 B:DC111 4.9 23.0 1.0
C32 A:0KL903 5.0 38.9 1.0

Reference:

K.Bergen, A.L.Steck, S.Strutt, A.Baccaro, W.Welte, K.Diederichs, A.Marx. Structures of Klentaq Dna Polymerase Caught While Incorporating C5-Modified Pyrimidine and C7-Modified 7-Deazapurine Nucleoside Triphosphates. J.Am.Chem.Soc. V. 134 11840 2012.
ISSN: ISSN 0002-7863
PubMed: 22475415
DOI: 10.1021/JA3017889
Page generated: Sun Jul 21 11:59:29 2024

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