Chlorine in PDB 4dkl: Crystal Structure of the Mu-Opioid Receptor Bound to A Morphinan Antagonist

All present enzymatic activity of Crystal Structure of the Mu-Opioid Receptor Bound to A Morphinan Antagonist:
3.2.1.17;

The structure of Crystal Structure of the Mu-Opioid Receptor Bound to A Morphinan Antagonist, PDB code: 4dkl was solved by A.Manglik, A.C.Kruse, T.S.Kobilka, F.S.Thian, J.M.Mathiesen, R.K.Sunahara, L.Pardo, W.I.Weis, B.K.Kobilka, S.Granier, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.49 / 2.80
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	70.882, 174.730, 68.353, 90.00, 107.84, 90.00
R / Rfree (%)	23.3 / 27.5

The binding sites of Chlorine atom in the Crystal Structure of the Mu-Opioid Receptor Bound to A Morphinan Antagonist (pdb code 4dkl). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the Mu-Opioid Receptor Bound to A Morphinan Antagonist, PDB code: 4dkl:

Chlorine binding site 1 out of 1 in the Crystal Structure of the Mu-Opioid Receptor Bound to A Morphinan Antagonist


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the Mu-Opioid Receptor Bound to A Morphinan Antagonist within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl618 b:90.8 occ:1.00 OG A:SER261 3.4 80.2 1.0 CB A:GLU270 3.4 97.1 1.0 N A:LYS271 3.7 87.6 1.0 CA A:GLU270 3.8 90.3 1.0 CG A:LYS271 4.0 96.0 1.0 C A:GLU270 4.2 86.6 1.0 CB A:SER261 4.3 88.8 1.0 OE1 A:GLU270 4.5 0.9 1.0 CE A:LYS271 4.5 0.3 1.0 CD A:LYS271 4.5 0.2 1.0 CA A:SER261 4.7 90.6 1.0 CG A:GLU270 4.7 1.0 1.0 CA A:LYS271 4.8 86.3 1.0 O A:LYS271 4.9 86.1 1.0 CB A:LYS271 4.9 89.8 1.0

A.Manglik, A.C.Kruse, T.S.Kobilka, F.S.Thian, J.M.Mathiesen, R.K.Sunahara, L.Pardo, W.I.Weis, B.K.Kobilka, S.Granier. Crystal Structure of the {Mu}-Opioid Receptor Bound to A Morphinan Antagonist. Nature V. 485 321 2012.
ISSN: ISSN 0028-0836
PubMed: 22437502
DOI: 10.1038/NATURE10954