Chlorine in PDB 4dtb: Crystal Structure of F95Y Aminoglycoside-2''-Phosphotransferase Type Iva in Complex with Guanosine

The structure of Crystal Structure of F95Y Aminoglycoside-2''-Phosphotransferase Type Iva in Complex with Guanosine, PDB code: 4dtb was solved by K.Shi, A.M.Berghuis, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	30.00 / 2.10
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	42.272, 101.341, 73.600, 90.00, 100.60, 90.00
R / Rfree (%)	19.7 / 25

The binding sites of Chlorine atom in the Crystal Structure of F95Y Aminoglycoside-2''-Phosphotransferase Type Iva in Complex with Guanosine (pdb code 4dtb). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of F95Y Aminoglycoside-2''-Phosphotransferase Type Iva in Complex with Guanosine, PDB code: 4dtb:

Chlorine binding site 1 out of 1 in the Crystal Structure of F95Y Aminoglycoside-2''-Phosphotransferase Type Iva in Complex with Guanosine


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of F95Y Aminoglycoside-2''-Phosphotransferase Type Iva in Complex with Guanosine within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl402 b:43.7 occ:1.00 O A:HOH543 3.4 4.6 1.0 CE1 A:HIS251 3.4 25.2 1.0 NZ A:LYS121 3.8 35.6 1.0 ND1 A:HIS251 3.8 25.2 1.0 CE A:LYS121 4.0 27.9 1.0 CD A:LYS121 4.2 27.1 1.0 NE2 A:HIS251 4.6 25.8 1.0 O A:HOH544 4.7 9.5 1.0

K.Shi, A.M.Berghuis. Structural Basis For Dual Nucleotide Selectivity of Aminoglycoside 2''-Phosphotransferase Iva Provides Insight on Determinants of Nucleotide Specificity of Aminoglycoside Kinases. J.Biol.Chem. V. 287 13094 2012.
ISSN: ISSN 0021-9258
PubMed: 22371504
DOI: 10.1074/JBC.M112.349670