Chlorine in PDB 4e83: Crystal Structure of Human Alpha-Defensin 5, HD5 (LEU29NLE Mutant)

The structure of Crystal Structure of Human Alpha-Defensin 5, HD5 (LEU29NLE Mutant), PDB code: 4e83 was solved by M.Pazgier, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.96 / 1.90
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	39.229, 60.772, 20.392, 90.00, 90.00, 90.00
R / Rfree (%)	19.9 / 24.3

The binding sites of Chlorine atom in the Crystal Structure of Human Alpha-Defensin 5, HD5 (LEU29NLE Mutant) (pdb code 4e83). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Alpha-Defensin 5, HD5 (LEU29NLE Mutant), PDB code: 4e83:

Chlorine binding site 1 out of 1 in the Crystal Structure of Human Alpha-Defensin 5, HD5 (LEU29NLE Mutant)


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Alpha-Defensin 5, HD5 (LEU29NLE Mutant) within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl101 b:48.2 occ:0.50 NH1 B:ARG6 3.3 50.0 1.0 CB B:ARG6 3.5 39.1 1.0 N B:THR7 3.5 43.6 1.0 CA B:ARG6 3.6 39.0 1.0 CD B:ARG6 3.6 39.1 1.0 CG B:ARG6 3.7 38.8 1.0 OG1 B:THR7 3.8 49.8 1.0 C B:ARG6 4.1 44.1 1.0 N B:GLY8 4.1 47.0 1.0 CZ B:ARG6 4.3 49.0 1.0 NE B:ARG6 4.4 41.1 1.0 CA B:THR7 4.5 45.9 1.0 CB B:THR7 4.6 51.0 1.0 C B:THR7 4.9 46.5 1.0 N B:ARG6 4.9 39.5 1.0 O B:CYS5 4.9 40.8 1.0

M.Rajabi, B.Ericksen, X.Wu, E.De Leeuw, L.Zhao, M.Pazgier, W.Lu. Functional Determinants of Human Enteric {Alpha}-Defensin HD5: Crucial Role For Hydrophobicity at Dimer Interface. J.Biol.Chem. V. 287 21615 2012.
ISSN: ISSN 0021-9258
PubMed: 22573326
DOI: 10.1074/JBC.M112.367995