Chlorine in PDB 4eei: Crystal Structure of Adenylosuccinate Lyase From Francisella Tularensis Complexed with Amp and Succinate

All present enzymatic activity of Crystal Structure of Adenylosuccinate Lyase From Francisella Tularensis Complexed with Amp and Succinate:
4.3.2.2;

The structure of Crystal Structure of Adenylosuccinate Lyase From Francisella Tularensis Complexed with Amp and Succinate, PDB code: 4eei was solved by N.Maltseva, Y.Kim, S.Shatsman, W.F.Anderson, A.Joachimiak, Center Forstructural Genomics Of Infectious Diseases (Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.33 / 1.92
Space group	P 43 21 2
Cell size a, b, c (Å), α, β, γ (°)	88.759, 88.759, 254.724, 90.00, 90.00, 90.00
R / Rfree (%)	16.8 / 19.9

The structure of Crystal Structure of Adenylosuccinate Lyase From Francisella Tularensis Complexed with Amp and Succinate also contains other interesting chemical elements:

Potassium

(K)

3 atoms

The binding sites of Chlorine atom in the Crystal Structure of Adenylosuccinate Lyase From Francisella Tularensis Complexed with Amp and Succinate (pdb code 4eei). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total 2 binding sites of Chlorine where determined in the Crystal Structure of Adenylosuccinate Lyase From Francisella Tularensis Complexed with Amp and Succinate, PDB code: 4eei:
Jump to Chlorine binding site number: 1; 2;

Chlorine binding site 1 out of 2 in the Crystal Structure of Adenylosuccinate Lyase From Francisella Tularensis Complexed with Amp and Succinate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Adenylosuccinate Lyase From Francisella Tularensis Complexed with Amp and Succinate within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl508 b:54.4 occ:1.00 OE2 B:GLU129 3.1 33.5 1.0 CD2 B:LEU125 3.6 20.6 1.0 CD B:ARG433 3.7 29.1 1.0 CG B:ARG433 3.8 32.2 1.0 CG1 B:VAL430 3.8 29.4 1.0 NE B:ARG433 3.8 28.3 1.0 CB B:ARG433 4.1 31.2 1.0 CD B:GLU129 4.1 32.1 1.0 CG B:LEU125 4.2 22.6 1.0 CD1 B:LEU125 4.5 25.1 1.0 CB B:VAL430 4.5 27.5 1.0 CG2 B:VAL430 4.5 26.4 1.0 CG B:GLU129 4.5 31.9 1.0

Chlorine binding site 2 out of 2 in the Crystal Structure of Adenylosuccinate Lyase From Francisella Tularensis Complexed with Amp and Succinate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 2 of Crystal Structure of Adenylosuccinate Lyase From Francisella Tularensis Complexed with Amp and Succinate within 5.0Å range: probe atom residue distance (Å) B Occ B:Cl509 b:56.7 occ:1.00 NH1 B:ARG433 2.6 25.9 1.0 O B:HOH874 2.9 37.5 1.0 CG B:ASP423 3.4 37.0 1.0 NH2 B:ARG433 3.4 27.2 1.0 CZ B:ARG433 3.5 30.3 1.0 OD1 B:ASP423 3.5 38.9 1.0 CB B:ASP423 3.6 30.0 1.0 CA B:ASP423 3.6 28.8 1.0 NZ B:LYS132 3.6 27.0 1.0 CE B:LYS132 3.7 25.1 1.0 O B:HOH786 3.8 45.3 1.0 OD2 B:ASP423 3.9 39.5 1.0 O B:ASP423 3.9 28.7 1.0 C B:ASP423 4.2 29.0 1.0 OD1 B:ASP427 4.3 28.8 1.0 O B:HOH860 4.4 33.8 1.0 O B:HOH757 4.5 54.8 1.0 OD2 B:ASP427 4.6 33.4 1.0 CG B:ASP427 4.6 33.2 1.0 CB B:PHE426 4.7 21.5 1.0 NE B:ARG433 4.7 28.3 1.0 N B:ASP423 4.8 26.4 1.0 CD B:LYS132 4.8 27.7 1.0

N.Maltseva, Y.Kim, S.Shatsman, W.F.Anderson, A.Joachimiak, Center For Structural Genomics Of Infectious Diseases(Csgid). Crystal Structure of Adenylosuccinate Lyase From Francisella Tularensis Complexed with Amp and Succinate To Be Published.