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Atomistry » Chlorine » PDB 4emw-4eu4 » 4enx » |
Chlorine in PDB 4enx: Crystal Structure of Pim-1 Kinase in Complex with Inhibitor (2E,5Z)-2- (2-Chlorophenylimino)-5-(4-Hydroxy-3-Nitrobenzylidene)Thiazolidin-4- OneEnzymatic activity of Crystal Structure of Pim-1 Kinase in Complex with Inhibitor (2E,5Z)-2- (2-Chlorophenylimino)-5-(4-Hydroxy-3-Nitrobenzylidene)Thiazolidin-4- One
All present enzymatic activity of Crystal Structure of Pim-1 Kinase in Complex with Inhibitor (2E,5Z)-2- (2-Chlorophenylimino)-5-(4-Hydroxy-3-Nitrobenzylidene)Thiazolidin-4- One:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of Pim-1 Kinase in Complex with Inhibitor (2E,5Z)-2- (2-Chlorophenylimino)-5-(4-Hydroxy-3-Nitrobenzylidene)Thiazolidin-4- One, PDB code: 4enx
was solved by
L.J.Parker,
N.Handa,
S.Yokoyama,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of Pim-1 Kinase in Complex with Inhibitor (2E,5Z)-2- (2-Chlorophenylimino)-5-(4-Hydroxy-3-Nitrobenzylidene)Thiazolidin-4- One
(pdb code 4enx). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Pim-1 Kinase in Complex with Inhibitor (2E,5Z)-2- (2-Chlorophenylimino)-5-(4-Hydroxy-3-Nitrobenzylidene)Thiazolidin-4- One, PDB code: 4enx: Chlorine binding site 1 out of 1 in 4enxGo back to Chlorine Binding Sites List in 4enx
Chlorine binding site 1 out
of 1 in the Crystal Structure of Pim-1 Kinase in Complex with Inhibitor (2E,5Z)-2- (2-Chlorophenylimino)-5-(4-Hydroxy-3-Nitrobenzylidene)Thiazolidin-4- One
Mono view Stereo pair view
Reference:
L.J.Parker,
H.Watanabe,
K.Tsuganezawa,
Y.Tomabechi,
N.Handa,
M.Shirouzu,
H.Yuki,
T.Honma,
N.Ogawa,
T.Nagano,
S.Yokoyama,
A.Tanaka.
Flexibility of the P-Loop of Pim-1 Kinase: Observation of A Novel Conformation Induced By Interaction with An Inhibitor Acta Crystallogr.,Sect.F V. 68 860 2012.
Page generated: Sat Dec 12 10:35:10 2020
ISSN: ESSN 1744-3091 PubMed: 22869110 DOI: 10.1107/S1744309112027108 |
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