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Atomistry » Chlorine » PDB 4emw-4eu4 » 4eqc | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Chlorine » PDB 4emw-4eu4 » 4eqc » |
Chlorine in PDB 4eqc: Crystal Structure of PAK1 Kinase Domain in Complex with FRAX597 InhibitorEnzymatic activity of Crystal Structure of PAK1 Kinase Domain in Complex with FRAX597 Inhibitor
All present enzymatic activity of Crystal Structure of PAK1 Kinase Domain in Complex with FRAX597 Inhibitor:
2.7.11.1; Protein crystallography data
The structure of Crystal Structure of PAK1 Kinase Domain in Complex with FRAX597 Inhibitor, PDB code: 4eqc
was solved by
J.Maksimoska,
R.Marmorstein,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of PAK1 Kinase Domain in Complex with FRAX597 Inhibitor
(pdb code 4eqc). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total 3 binding sites of Chlorine where determined in the Crystal Structure of PAK1 Kinase Domain in Complex with FRAX597 Inhibitor, PDB code: 4eqc: Jump to Chlorine binding site number: 1; 2; 3; Chlorine binding site 1 out of 3 in 4eqcGo back to Chlorine Binding Sites List in 4eqc
Chlorine binding site 1 out
of 3 in the Crystal Structure of PAK1 Kinase Domain in Complex with FRAX597 Inhibitor
Mono view Stereo pair view
Chlorine binding site 2 out of 3 in 4eqcGo back to Chlorine Binding Sites List in 4eqc
Chlorine binding site 2 out
of 3 in the Crystal Structure of PAK1 Kinase Domain in Complex with FRAX597 Inhibitor
Mono view Stereo pair view
Chlorine binding site 3 out of 3 in 4eqcGo back to Chlorine Binding Sites List in 4eqc
Chlorine binding site 3 out
of 3 in the Crystal Structure of PAK1 Kinase Domain in Complex with FRAX597 Inhibitor
Mono view Stereo pair view
Reference:
S.Licciulli,
J.Maksimoska,
C.Zhou,
S.Troutman,
S.Kota,
Q.Liu,
S.Duron,
D.Campbell,
J.Chernoff,
J.Field,
R.Marmorstein,
J.L.Kissil.
FRAX597, A Small Molecule Inhibitor of the P21-Activated Kinases, Inhibits Tumorigenesis of Neurofibromatosis Type 2 (NF2)-Associated Schwannomas. J.Biol.Chem. V. 288 29105 2013.
Page generated: Sat Dec 12 10:35:20 2020
ISSN: ISSN 0021-9258 PubMed: 23960073 DOI: 10.1074/JBC.M113.510933 |
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