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Atomistry » Chlorine » PDB 4eu6-4f1a » 4ewq » |
Chlorine in PDB 4ewq: Human P38 Alpha Mapk in Complex with A Pyridazine Based InhibitorEnzymatic activity of Human P38 Alpha Mapk in Complex with A Pyridazine Based Inhibitor
All present enzymatic activity of Human P38 Alpha Mapk in Complex with A Pyridazine Based Inhibitor:
2.7.11.24; Protein crystallography data
The structure of Human P38 Alpha Mapk in Complex with A Pyridazine Based Inhibitor, PDB code: 4ewq
was solved by
V.Grum-Tokars,
G.Minasov,
S.Roy,
J.Schavocky,
J.Winsor,
D.M.Watterson,
W.F.Anderson,
Center For Structural Genomics Of Infectious Diseases(Csgid),
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4ewq:
The structure of Human P38 Alpha Mapk in Complex with A Pyridazine Based Inhibitor also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Human P38 Alpha Mapk in Complex with A Pyridazine Based Inhibitor
(pdb code 4ewq). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Human P38 Alpha Mapk in Complex with A Pyridazine Based Inhibitor, PDB code: 4ewq: Chlorine binding site 1 out of 1 in 4ewqGo back to![]() ![]()
Chlorine binding site 1 out
of 1 in the Human P38 Alpha Mapk in Complex with A Pyridazine Based Inhibitor
![]() Mono view ![]() Stereo pair view
Reference:
S.M.Roy,
G.Minasov,
O.Arancio,
L.W.Chico,
L.J.Van Eldik,
W.F.Anderson,
J.C.Pelletier,
D.M.Watterson.
A Selective and Brain Penetrant P38 Alpha Mapk Inhibitor Candidate For Neurologic and Neuropsychiatric Disorders That Attenuates Neuroinflammation and Cognitive Dysfunction. J.Med.Chem. V. 62 5298 2019.
Page generated: Fri Jul 11 15:04:29 2025
ISSN: ISSN 0022-2623 PubMed: 30978288 DOI: 10.1021/ACS.JMEDCHEM.9B00058 |
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