Chlorine in PDB 4f40: X-Ray Crystal Structure of Apo Prostaglandin F Synthase From Leishmania Major Friedlin

All present enzymatic activity of X-Ray Crystal Structure of Apo Prostaglandin F Synthase From Leishmania Major Friedlin:
1.1.1.188;

The structure of X-Ray Crystal Structure of Apo Prostaglandin F Synthase From Leishmania Major Friedlin, PDB code: 4f40 was solved by Seattle Structural Genomics Center For Infectious Disease (Ssgcid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.19 / 1.60
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	94.550, 34.590, 107.200, 90.00, 103.22, 90.00
R / Rfree (%)	15.4 / 18

The binding sites of Chlorine atom in the X-Ray Crystal Structure of Apo Prostaglandin F Synthase From Leishmania Major Friedlin (pdb code 4f40). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the X-Ray Crystal Structure of Apo Prostaglandin F Synthase From Leishmania Major Friedlin, PDB code: 4f40:

Chlorine binding site 1 out of 1 in the X-Ray Crystal Structure of Apo Prostaglandin F Synthase From Leishmania Major Friedlin


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of X-Ray Crystal Structure of Apo Prostaglandin F Synthase From Leishmania Major Friedlin within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl311 b:49.9 occ:1.00 N A:GLU261 2.8 20.6 1.0 O A:HOH462 2.8 23.8 1.0 CB A:GLU261 3.2 21.5 1.0 N A:ALA260 3.5 18.4 1.0 CA A:GLU261 3.5 20.1 1.0 O A:HOH565 3.7 30.9 1.0 C A:ALA260 3.8 20.5 1.0 CA A:ALA260 3.9 19.3 1.0 CB A:ALA260 4.0 24.4 1.0 C A:GLY259 4.0 18.2 1.0 O A:HOH713 4.4 41.2 1.0 CA A:GLY259 4.4 19.5 1.0 N A:ASP262 4.5 15.3 1.0 C A:GLU261 4.6 16.2 1.0 O A:GLY259 4.7 19.0 1.0 O A:ALA260 4.9 15.4 1.0

S.O.Moen, J.W.Fairman, S.R.Barnes, A.Sullivan, S.Nakazawa-Hewitt, W.C.Van Voorhis, B.L.Staker, D.D.Lorimer, P.J.Myler, T.E.Edwards. Structures of Prostaglandin F Synthase From the Protozoa Leishmania Major and Trypanosoma Cruzi with Nadp. Acta Crystallogr F Struct V. 71 609 2015BIOL Commun.
ISSN: ISSN 1744-3091
PubMed: 25945716
DOI: 10.1107/S2053230X15006883