Chlorine in PDB 4fko: Crystal Structure of the CDK2 in Complex with Thiazolylpyrimidine Inhibitor

All present enzymatic activity of Crystal Structure of the CDK2 in Complex with Thiazolylpyrimidine Inhibitor:
2.7.11.22;

The structure of Crystal Structure of the CDK2 in Complex with Thiazolylpyrimidine Inhibitor, PDB code: 4fko was solved by Y.N.Kang, J.A.Stuckey, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	32.11 / 1.55
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	53.459, 71.780, 71.897, 90.00, 90.00, 90.00
R / Rfree (%)	17.6 / 19.9

The binding sites of Chlorine atom in the Crystal Structure of the CDK2 in Complex with Thiazolylpyrimidine Inhibitor (pdb code 4fko). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the CDK2 in Complex with Thiazolylpyrimidine Inhibitor, PDB code: 4fko:

Chlorine binding site 1 out of 1 in the Crystal Structure of the CDK2 in Complex with Thiazolylpyrimidine Inhibitor


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of the CDK2 in Complex with Thiazolylpyrimidine Inhibitor within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl301 b:29.7 occ:1.00 CL A:20K301 0.0 29.7 1.0 C16 A:20K301 1.7 23.8 1.0 C17 A:20K301 2.7 21.6 1.0 C13 A:20K301 2.7 22.2 1.0 N4 A:20K301 3.0 26.5 1.0 O A:HIS84 3.4 24.0 1.0 C15 A:20K301 3.4 30.8 1.0 O A:HOH496 3.6 35.3 1.0 O A:HOH422 3.9 21.1 1.0 O A:HOH553 3.9 25.5 1.0 C10 A:20K301 4.0 18.1 1.0 C12 A:20K301 4.0 19.3 1.0 O A:HOH474 4.2 43.4 1.0 C A:HIS84 4.3 23.4 1.0 CZ A:PHE82 4.4 22.5 1.0 C14 A:20K301 4.5 30.0 1.0 C11 A:20K301 4.5 18.8 1.0 CG2 A:ILE10 4.6 27.3 1.0 CA A:GLN85 4.7 18.9 1.0 N A:GLN85 4.9 18.5 1.0 CE1 A:PHE82 4.9 22.8 1.0

Y.N.Kang, J.A.Stuckey. Crystal Structure of the CDK2 in Complex with Thiazolylpyrimidine Inhibitor To Be Published.