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Atomistry » Chlorine » PDB 4fm6-4fuy » 4fny » |
Chlorine in PDB 4fny: Crystal Structure of the R1275Q Anaplastic Lymphoma Kinase Catalytic Domain in Complex with A Benzoxazole InhibitorEnzymatic activity of Crystal Structure of the R1275Q Anaplastic Lymphoma Kinase Catalytic Domain in Complex with A Benzoxazole Inhibitor
All present enzymatic activity of Crystal Structure of the R1275Q Anaplastic Lymphoma Kinase Catalytic Domain in Complex with A Benzoxazole Inhibitor:
2.7.10.1; Protein crystallography data
The structure of Crystal Structure of the R1275Q Anaplastic Lymphoma Kinase Catalytic Domain in Complex with A Benzoxazole Inhibitor, PDB code: 4fny
was solved by
D.A.Whittington,
L.F.Epstein,
H.Chen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of the R1275Q Anaplastic Lymphoma Kinase Catalytic Domain in Complex with A Benzoxazole Inhibitor
(pdb code 4fny). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of the R1275Q Anaplastic Lymphoma Kinase Catalytic Domain in Complex with A Benzoxazole Inhibitor, PDB code: 4fny: Chlorine binding site 1 out of 1 in 4fnyGo back to Chlorine Binding Sites List in 4fny
Chlorine binding site 1 out
of 1 in the Crystal Structure of the R1275Q Anaplastic Lymphoma Kinase Catalytic Domain in Complex with A Benzoxazole Inhibitor
Mono view Stereo pair view
Reference:
L.F.Epstein,
H.Chen,
R.Emkey,
D.A.Whittington.
The R1275Q Neuroblastoma Mutant and Certain Atp-Competitive Inhibitors Stabilize Alternative Activation Loop Conformations of Anaplastic Lymphoma Kinase. J.Biol.Chem. V. 287 37447 2012.
Page generated: Sat Dec 12 10:37:45 2020
ISSN: ISSN 0021-9258 PubMed: 22932897 DOI: 10.1074/JBC.M112.391425 |
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