Chlorine in PDB 4gcd: Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 2

Enzymatic activity of Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 2

All present enzymatic activity of Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 2:
3.2.1.17;

Protein crystallography data

The structure of Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 2, PDB code: 4gcd was solved by J.R.Helliwell, S.W.M.Tanley, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

*Resolution Low / High (Å)*	35.74 / 2.80
*Space group*	P 4₃ 2₁ 2
*Cell size a, b, c (Å), α, β, γ (°)*	79.863, 79.863, 37.802, 90.00, 90.00, 90.00
*R / R_free (%)*	17.5 / 24

Other elements in 4gcd:

The structure of Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 2 also contains other interesting chemical elements:

Platinum

(Pt)

2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 2 (pdb code 4gcd). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 2, PDB code: 4gcd:

Chlorine binding site 1 out of 1 in 4gcd

Go back to

Chlorine Binding Sites List in 4gcd

Chlorine binding site 1 out of 1 in the Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 2

Mono view

Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 2 within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
A:Cl204 b:45.6 occ:0.66	CL2	A:CPT204	0.0	45.6	0.7
	PT1	A:CPT204	2.4	64.2	0.7
	OD1	A:ASN93	2.7	36.2	1.0
	N2	A:CPT204	3.0	58.9	0.7
	ND1	A:HIS15	3.3	49.2	1.0
	CG	A:ASN93	3.8	34.9	1.0
	CG1	A:VAL92	3.9	25.4	1.0
	NZ	A:LYS96	3.9	37.8	1.0
	O	A:HIS15	3.9	40.1	1.0
	CG	A:HIS15	4.3	46.2	1.0
	CG2	A:THR89	4.3	33.0	1.0
	CE1	A:HIS15	4.3	50.1	1.0
	ND2	A:ASN93	4.3	37.4	1.0
	CB	A:HIS15	4.3	43.6	1.0
	O	A:THR89	4.4	29.9	1.0
	CA	A:HIS15	4.5	43.0	1.0
	C	A:HIS15	4.6	41.4	1.0
	CB	A:VAL92	4.6	24.8	1.0
	N	A:ASN93	4.7	27.2	1.0
	CE	A:LYS96	4.7	35.5	1.0
	CA	A:THR89	5.0	30.3	1.0
	CB	A:ASN93	5.0	31.8	1.0

Reference:

J.R.Helliwell, S.W.Tanley. The Crystal Structure Analysis of the Relative Binding of Cisplatin and Carboplatin in A Mixture with Histidine in A Protein Studied at 100 and 300 K with Repeated X-Ray Irradiation. Acta Crystallogr.,Sect.D V. 69 121 2013.
ISSN: ISSN 0907-4449
PubMed: 23275170
DOI: 10.1107/S090744491204423X

Page generated: Wed Oct 28 11:44:45 2020

Last articles

Xe in 6AYK
Xe in 6QII
Xe in 6ASM
Xe in 5NSW
Xe in 6FY9
Xe in 5O1K
Xe in 5O27
Xe in 5M69
Xe in 5KPU
Xe in 5I63

	© Copyright 2008-2020 by atomistry.com
Home \| Site Map \| Copyright \| Contact us \| Privacy