Atomistry » Chlorine » PDB 4g81-4gen » 4gce
Atomistry »
  Chlorine »
    PDB 4g81-4gen »
      4gce »

Chlorine in PDB 4gce: Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 3

Enzymatic activity of Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 3

All present enzymatic activity of Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 3:
3.2.1.17;

Protein crystallography data

The structure of Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 3, PDB code: 4gce was solved by J.R.Helliwell, S.W.M.Tanley, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 56.47 / 2.90
Space group P 43 21 2
Cell size a, b, c (Å), α, β, γ (°) 79.863, 79.863, 37.802, 90.00, 90.00, 90.00
R / Rfree (%) 17.4 / 23.4

Other elements in 4gce:

The structure of Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 3 also contains other interesting chemical elements:

Platinum (Pt) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 3 (pdb code 4gce). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 3, PDB code: 4gce:

Chlorine binding site 1 out of 1 in 4gce

Go back to Chlorine Binding Sites List in 4gce
Chlorine binding site 1 out of 1 in the Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 3


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Room Temperature X-Ray Diffraction Study of A 6-Fold Molar Excess of A Cisplatin/Carboplatin Mixture Binding to Hewl, Dataset 3 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl202

b:51.3
occ:0.60
CL2 A:CPT202 0.0 51.3 0.6
PT1 A:CPT202 2.4 61.5 0.6
OD1 A:ASN93 2.6 32.9 1.0
ND1 A:HIS15 3.6 42.1 1.0
CG A:ASN93 3.7 31.2 1.0
O A:HIS15 3.8 38.5 1.0
CG2 A:THR89 4.1 30.2 1.0
CG1 A:VAL92 4.1 22.8 1.0
ND2 A:ASN93 4.2 33.6 1.0
CB A:HIS15 4.3 37.6 1.0
CG A:HIS15 4.3 39.2 1.0
NZ A:LYS96 4.4 29.5 1.0
N1 A:CPT202 4.5 52.6 0.6
O A:THR89 4.5 26.8 1.0
CE1 A:HIS15 4.6 43.5 1.0
CA A:HIS15 4.6 38.9 1.0
C A:HIS15 4.6 38.5 1.0
N A:ASN93 4.8 23.9 1.0
CE A:LYS96 4.8 27.8 1.0
CB A:VAL92 4.8 21.9 1.0
CB A:ASN93 5.0 28.6 1.0

Reference:

J.R.Helliwell, S.W.Tanley. The Crystal Structure Analysis of the Relative Binding of Cisplatin and Carboplatin in A Mixture with Histidine in A Protein Studied at 100 and 300 K with Repeated X-Ray Irradiation. Acta Crystallogr.,Sect.D V. 69 121 2013.
ISSN: ISSN 0907-4449
PubMed: 23275170
DOI: 10.1107/S090744491204423X
Page generated: Fri Jul 11 15:36:04 2025

Last articles

Fe in 2YXO
Fe in 2YRS
Fe in 2YXC
Fe in 2YNM
Fe in 2YVJ
Fe in 2YP1
Fe in 2YU2
Fe in 2YU1
Fe in 2YQB
Fe in 2YOO
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy