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Chlorine in PDB 4h1n: Crystal Structure of P450 2B4 F297A Mutant in Complex with Anti- Platelet Drug ClopidogrelEnzymatic activity of Crystal Structure of P450 2B4 F297A Mutant in Complex with Anti- Platelet Drug Clopidogrel
All present enzymatic activity of Crystal Structure of P450 2B4 F297A Mutant in Complex with Anti- Platelet Drug Clopidogrel:
1.14.14.1; Protein crystallography data
The structure of Crystal Structure of P450 2B4 F297A Mutant in Complex with Anti- Platelet Drug Clopidogrel, PDB code: 4h1n
was solved by
M.B.Shah,
H.H.Jang,
C.D.Stout,
J.R.Halpert,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4h1n:
The structure of Crystal Structure of P450 2B4 F297A Mutant in Complex with Anti- Platelet Drug Clopidogrel also contains other interesting chemical elements:
Chlorine Binding Sites:
The binding sites of Chlorine atom in the Crystal Structure of P450 2B4 F297A Mutant in Complex with Anti- Platelet Drug Clopidogrel
(pdb code 4h1n). This binding sites where shown within
5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of P450 2B4 F297A Mutant in Complex with Anti- Platelet Drug Clopidogrel, PDB code: 4h1n: Chlorine binding site 1 out of 1 in 4h1nGo back to Chlorine Binding Sites List in 4h1n
Chlorine binding site 1 out
of 1 in the Crystal Structure of P450 2B4 F297A Mutant in Complex with Anti- Platelet Drug Clopidogrel
Mono view Stereo pair view
Reference:
M.B.Shah,
H.H.Jang,
Q.Zhang,
C.David Stout,
J.R.Halpert.
X-Ray Crystal Structure of the Cytochrome P450 2B4 Active Site Mutant F297A in Complex with Clopidogrel: Insights Into Compensatory Rearrangements of the Binding Pocket. Arch.Biochem.Biophys. V. 530 64 2013.
Page generated: Sat Dec 12 10:41:18 2020
ISSN: ISSN 0003-9861 PubMed: 23296089 DOI: 10.1016/J.ABB.2012.12.016 |
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