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Chlorine in PDB 4he1: Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Fructose-6-Phosphate and Phosphate

Enzymatic activity of Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Fructose-6-Phosphate and Phosphate

All present enzymatic activity of Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Fructose-6-Phosphate and Phosphate:
3.1.3.11;

Protein crystallography data

The structure of Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Fructose-6-Phosphate and Phosphate, PDB code: 4he1 was solved by R.Shi, D.W.Zhu, S.X.Lin, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 50.00 / 2.23
Space group P 42 21 2
Cell size a, b, c (Å), α, β, γ (°) 73.818, 73.818, 146.575, 90.00, 90.00, 90.00
R / Rfree (%) 19.3 / 21.1

Other elements in 4he1:

The structure of Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Fructose-6-Phosphate and Phosphate also contains other interesting chemical elements:

Magnesium (Mg) 2 atoms

Chlorine Binding Sites:

The binding sites of Chlorine atom in the Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Fructose-6-Phosphate and Phosphate (pdb code 4he1). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Fructose-6-Phosphate and Phosphate, PDB code: 4he1:

Chlorine binding site 1 out of 1 in 4he1

Go back to Chlorine Binding Sites List in 4he1
Chlorine binding site 1 out of 1 in the Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Fructose-6-Phosphate and Phosphate


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Crystal Structure of Human Muscle Fructose-1,6-Bisphosphatase Q32R Mutant Complex with Fructose-6-Phosphate and Phosphate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Cl405

b:46.9
occ:0.50
OG A:SER131 3.3 31.2 1.0
N A:SER131 3.3 30.0 1.0
CB A:ALA130 3.7 31.9 1.0
CG1 A:VAL245 3.8 16.1 1.0
CB A:SER131 3.8 29.5 1.0
CA A:ALA130 3.9 31.6 1.0
C A:ALA130 4.1 30.8 1.0
CA A:SER131 4.2 29.5 1.0
CG2 A:VAL245 4.4 16.0 1.0
CB A:VAL245 4.8 17.2 1.0

Reference:

R.Shi, Z.Y.Chen, D.W.Zhu, C.Li, Y.Shan, G.Xu, S.X.Lin. Crystal Structures of Human Muscle Fructose-1,6-Bisphosphatase: Novel Quaternary States, Enhanced Amp Affinity, and Allosteric Signal Transmission Pathway. Plos One V. 8 71242 2013.
ISSN: ESSN 1932-6203
PubMed: 24086250
DOI: 10.1371/JOURNAL.PONE.0071242
Page generated: Sat Dec 12 10:42:33 2020

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