Chlorine in PDB 4hvl: Structure of A Serine Protease MYCP1, An Essential Component of the Type VII (Esx-1) Secretion System

The structure of Structure of A Serine Protease MYCP1, An Essential Component of the Type VII (Esx-1) Secretion System, PDB code: 4hvl was solved by K.V.Korotkov, T.J.Evans, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.92 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	61.950, 73.080, 75.420, 90.00, 90.00, 90.00
R / Rfree (%)	16.9 / 20.6

The structure of Structure of A Serine Protease MYCP1, An Essential Component of the Type VII (Esx-1) Secretion System also contains other interesting chemical elements:

Zinc

(Zn)

7 atoms

The binding sites of Chlorine atom in the Structure of A Serine Protease MYCP1, An Essential Component of the Type VII (Esx-1) Secretion System (pdb code 4hvl). This binding sites where shown within 5.0 Angstroms radius around Chlorine atom.
In total only one binding site of Chlorine was determined in the Structure of A Serine Protease MYCP1, An Essential Component of the Type VII (Esx-1) Secretion System, PDB code: 4hvl:

Chlorine binding site 1 out of 1 in the Structure of A Serine Protease MYCP1, An Essential Component of the Type VII (Esx-1) Secretion System


Mono view


Stereo pair view

A full contact list of Chlorine with other atoms in the Cl binding site number 1 of Structure of A Serine Protease MYCP1, An Essential Component of the Type VII (Esx-1) Secretion System within 5.0Å range: probe atom residue distance (Å) B Occ A:Cl513 b:20.0 occ:0.85 ZN A:ZN501 2.4 20.3 0.8 CA A:ASP92 3.4 15.3 1.0 O A:ASP92 3.7 15.4 1.0 N A:GLU203 3.7 17.1 1.0 OG1 A:THR156 3.7 21.6 1.0 CB A:GLU203 3.7 19.1 1.0 O A:ILE91 3.7 14.4 1.0 N A:ASP92 3.7 15.2 1.0 OE1 A:GLU203 3.8 23.2 1.0 C A:ASP92 3.8 15.3 1.0 CA A:GLU203 3.8 18.2 1.0 ND1 A:HIS155 3.9 19.3 1.0 CB A:THR156 3.9 19.5 1.0 C A:ILE91 3.9 14.9 1.0 CB A:HIS155 4.0 16.4 1.0 O A:HOH809 4.0 45.6 1.0 N A:THR156 4.1 17.0 1.0 C A:SER202 4.3 16.1 1.0 CG A:HIS155 4.4 17.8 1.0 CB A:SER202 4.5 15.7 1.0 CG2 A:ILE91 4.5 15.8 1.0 C A:HIS155 4.6 17.2 1.0 CD A:GLU203 4.7 22.1 1.0 CA A:THR156 4.7 18.4 1.0 CA A:HIS155 4.7 16.1 1.0 CG A:GLU203 4.7 20.3 1.0 CB A:ASP92 4.8 15.8 1.0 CA A:SER202 4.8 15.4 1.0 N A:THR93 4.8 15.0 1.0 N A:HIS155 4.9 14.3 1.0 N A:SER202 4.9 14.6 1.0 O A:SER202 5.0 16.6 1.0 CE1 A:HIS155 5.0 19.5 1.0

J.M.Wagner, T.J.Evans, J.Chen, H.Zhu, E.N.Houben, W.Bitter, K.V.Korotkov. Understanding Specificity of the Mycosin Proteases in Esx/Type VII Secretion By Structural and Functional Analysis. J.Struct.Biol. V. 184 115 2013.
ISSN: ISSN 1047-8477
PubMed: 24113528
DOI: 10.1016/J.JSB.2013.09.022